货号:A166579 同义名: 鲁米诺 / Diogenes reagent;3-Aminophthalhydrazide
Luminol is a chemical with chemiluminescence property, soluble in most polar organic solvents, insoluble in water. When mixed with an appropriate oxidizing agent, it emits a blue glow.
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免费溶解
产品名称 | FAAH ↓ ↑ | 其他靶点 | 纯度 | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
URB-597 |
++++
FAAH, IC50: 4.6 nM |
99% | |||||||||||||||||
JNJ-1661010 |
+++
FAAH (rat), IC50: 10 nM FAAH (human), IC50: 12 nM |
99% | |||||||||||||||||
Biochanin A |
+
FAAH (human), IC50: 1.4 μM FAAH (mouse), IC50: 1.8 μM |
EGFR | 98+% | ||||||||||||||||
PF-3845 |
++
FAAH, Ki: 230 nM |
99%+ | |||||||||||||||||
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。 |
描述 | Luminol is a major probe for chemiluminescence (CL) and electrochemiluminescence (ECL) detection technologies in (bio)analysis. LCL (luminol chemiluminescence) is a very useful detection method due to its selectivity, simplicity, low cost, and high sensitivity. LCL has a dynamic range of applications, including quantification and detection of macro and micromolecules such as proteins, carbohydrates, DNA, and RNA. Luminol-based methods are used in environmental monitoring as biosensors, in the pharmaceutical industry for cellular localization and as biological tracers, and in reporter gene-based assays and several other immunoassays[1]. Moreover, a significant peak in chemiluminescence production in a particle-free system occurs between 5 and 15 min following exposure of cells to micromolar concentrations of luminol. The response is directly related to dose over a wide rane of luminol concentrations and can be inhibited by superoxide dismutase (90%), catalase (100%) and sodium azide (40%). The effect of luminol eliciting a peak in neutrophil chemiluminescence is mediated within intact cells rather than at the cell membrane. Luminol may produce a peak in chemiluminescence by stimulating very low levels of hexose monophosphate shunt activity and superoxide generation or it may simply amplify light production generated by the production of excited oxygen radicals resulting from surface interactions[2]. |
计算器 | ||||
存储液制备 | 1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
5.64mL 1.13mL 0.56mL |
28.22mL 5.64mL 2.82mL |
56.45mL 11.29mL 5.64mL |
CAS号 | 521-31-3 |
分子式 | C8H7N3O2 |
分子量 | 177.16 |
别名 | 鲁米诺 ;Diogenes reagent;3-Aminophthalhydrazide;NSC 5064 |
运输 | 蓝冰 |
存储条件 |
液体 -20°C:3-6个月-80°C:12个月 粉末 Keep in dark place,Sealed in dry,Room Temperature |
溶解度 |
DMSO: 30 mg/mL(169.34 mM),注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO |
动物实验配方 |