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鲁米诺 /Luminol {[allProObj[0].p_purity_real_show]}

货号:A166579 同义名: 鲁米诺 / Diogenes reagent;3-Aminophthalhydrazide

Luminol is a chemical with chemiluminescence property, soluble in most polar organic solvents, insoluble in water. When mixed with an appropriate oxidizing agent, it emits a blue glow.

Luminol 化学结构 CAS号:521-31-3
Luminol 化学结构
CAS号:521-31-3
Luminol 3D分子结构
CAS号:521-31-3
Luminol 化学结构 CAS号:521-31-3
Luminol 3D分子结构 CAS号:521-31-3
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Luminol 纯度/质量文件 产品仅供科研

货号:A166579 标准纯度: {[allProObj[0].p_purity_real_show]}
批次查询: 批次纯度:

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产品名称 FAAH 其他靶点 纯度
URB-597 ++++

FAAH, IC50: 4.6 nM

99%
JNJ-1661010 +++

FAAH (human), IC50: 12 nM

FAAH (rat), IC50: 10 nM

99%
Biochanin A +

FAAH (mouse), IC50: 1.8 μM

FAAH (human), IC50: 1.4 μM

EGFR 98+%
PF-3845 ++

FAAH, Ki: 230 nM

99%+
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。

Luminol 生物活性

描述 Luminol is a major probe for chemiluminescence (CL) and electrochemiluminescence (ECL) detection technologies in (bio)analysis. LCL (luminol chemiluminescence) is a very useful detection method due to its selectivity, simplicity, low cost, and high sensitivity. LCL has a dynamic range of applications, including quantification and detection of macro and micromolecules such as proteins, carbohydrates, DNA, and RNA. Luminol-based methods are used in environmental monitoring as biosensors, in the pharmaceutical industry for cellular localization and as biological tracers, and in reporter gene-based assays and several other immunoassays[1]. Moreover, a significant peak in chemiluminescence production in a particle-free system occurs between 5 and 15 min following exposure of cells to micromolar concentrations of luminol. The response is directly related to dose over a wide rane of luminol concentrations and can be inhibited by superoxide dismutase (90%), catalase (100%) and sodium azide (40%). The effect of luminol eliciting a peak in neutrophil chemiluminescence is mediated within intact cells rather than at the cell membrane. Luminol may produce a peak in chemiluminescence by stimulating very low levels of hexose monophosphate shunt activity and superoxide generation or it may simply amplify light production generated by the production of excited oxygen radicals resulting from surface interactions[2].

Luminol 参考文献

[1]Khan P, Idrees D, Moxley MA, Corbett JA, Ahmad F, von Figura G, Sly WS, Waheed A, Hassan MI. Luminol-based chemiluminescent signals: clinical and non-clinical application and future uses. Appl Biochem Biotechnol. 2014 May;173(2):333-55.

[2]Allred CD, Margetts J, Hill HR. Luminol-induced neutrophil chemiluminescence. Biochim Biophys Acta. 1980 Aug 13;631(2):380-5.

Luminol 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

5.64mL

1.13mL

0.56mL

28.22mL

5.64mL

2.82mL

56.45mL

11.29mL

5.64mL

Luminol 技术信息

CAS号521-31-3
分子式C8H7N3O2
分子量 177.16
别名 鲁米诺 ;Diogenes reagent;3-Aminophthalhydrazide;NSC 5064
运输蓝冰
存储条件

液体 -20°C:3-6个月-80°C:12个月

粉末 Keep in dark place,Sealed in dry,Room Temperature

溶解度

DMSO: 30 mg/mL(169.34 mM),注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方
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