LY 2389575 HCl is a selective negative allosteric modulator of mGlu3 with IC50 of 190 nM.
规格 | 价格 | 会员价 | 库存 | 数量 | |||
---|---|---|---|---|---|---|---|
{[ item.pr_size ]} |
{[ getRatePrice(item.pr_rmb, 1,1) ]} {[ getRatePrice(item.pr_rmb_sale, 1,1) ]} |
{[ getRatePrice(item.pr_rmb, 1,1) ]} {[ getRatePrice(item.pr_rmb,item.pr_rate,1) ]} |
{[ getRatePrice(item.pr_rmb, 1,1) ]} | {[ getRatePrice(item.pr_rmb_sale, 1,1) ]} {[ getRatePrice(item.pr_rmb,item.pr_rate,item.mem_rate) ]} {[ getRatePrice(item.pr_rmb,1,item.mem_rate) ]} | 现货 | 咨询 | - + |
快速发货 顺丰冷链运输,1-2 天到达
品质保证
技术支持
免费溶解
描述 | LY2389575 hydrochloride is a selective and non-competitive mGlu3 negative allosteric modulator (NAM) with an IC50 value of 190 nM. LY2389575 hydrochloride induces an increase in the level of Mrc1. LY2389575 hydrochloride also independently amplifies the toxicity of amyloid beta (Aβ), which can be used in Alzheimer's disease research[1][2][3].At a concentration of 5 μM, treatment for 1 hour, LY2389575 hydrochloride induces elevated levels of Mrc1 in microglia[2]. |
计算器 | ||||
存储液制备 | 1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
2.28mL 0.46mL 0.23mL |
11.40mL 2.28mL 1.14mL |
22.80mL 4.56mL 2.28mL |
CAS号 | 885104-09-6 |
分子式 | C15H16BrCl3N4 |
分子量 | 438.577 |
别名 | |
运输 | 蓝冰 |
存储条件 |
粉末 Inert atmosphere,2-8°C 液体 -20°C:3-6个月-80°C:12个月 |
溶解度 |
DMSO: 105 mg/mL(239.41 mM),配合低频超声,并水浴加热至45℃助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO |
动物实验配方 |