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胰岛素(人) /Insulin (human) {[allProObj[0].p_purity_real_show]}

货号:A208403 同义名: 胰岛素(人) / Insulin regular;Insulin

Insulin, Human is a two-chain polypeptide hormone produced by the β-cells of pancreatic islets, it regulates the cellular uptake, utilization, and storage of glucose, amino acids, and fatty acids and inhibits the breakdown of glycogen, protein, and fat.

Insulin (human) 化学结构 CAS号:11061-68-0
Insulin (human) 化学结构
CAS号:11061-68-0
Insulin (human) 3D分子结构
CAS号:11061-68-0
Insulin (human) 化学结构 CAS号:11061-68-0
Insulin (human) 3D分子结构 CAS号:11061-68-0
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Insulin (human) 纯度/质量文件 产品仅供科研

货号:A208403 标准纯度: {[allProObj[0].p_purity_real_show]}
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产品名称 IGF-1R Insulin Receptor 其他靶点 纯度
BMS-536924 ++

IGF-1R, IC50: 100 nM

+++

Insulin Receptor, IC50: 73 nM

FAK,MEK 98%
GSK1904529A +++

IGF-1R, IC50: 27 nM

+++

Insulin Receptor, IC50: 25 nM

98+%
Picropodophyllin ++++

IGF-1R, IC50: 1 nM

99%+
NVP-AEW541 ++

IGF-1R, IC50: 0.15 μM

++

Insulin Receptor, IC50: 0.14 μM

FLT3 99%+
NVP-ADW742 +

IGF-1R, IC50: 0.17 μM

99%
GSK1838705A +++

IGF-1R, IC50: 2 nM

++++

Insulin Receptor, IC50: 1.6 nM

ALK 99%
BMS-754807 ++++

IGF-1R, IC50: 1.8 nM

++++

Insulin Receptor, IC50: 1.7 nM

99%+
Linsitinib +++

IGF-1R, IC50: 35 nM

++

Insulin Receptor, IC50: 75 nM

99%+
AG1024 +

IGF-1R, IC50: 7 μM

+

Insulin Receptor, IC50: 57 μM

98%
PQ401 +

IGF-1R, IC50: <1 μM

99%+
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。

Insulin (human) 生物活性

描述 Insulin, Human is a two-chain polypeptide hormone produced by the β-cells of pancreatic islets, it regulates the cellular uptake, utilization, and storage of glucose, amino acids, and fatty acids and inhibits the breakdown of glycogen, protein, and fat.
Insulin should be solubilized in dilute acetic (1%) or hydrochloric acid, pH 2-3, with solubility of 1-10 mg/mL. The stock solution of Insulin should be stored frozen at -20°C in single-use aliquots to avoid freeze-thaw cycles.

Insulin (human) 临床研究

NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT01951716 Does the Vagus Nerve Mediate t... 展开 >>he Effects of Xenin-25 收起 << Phase 1 Withdrawn July 2018 United States, Missouri ... 展开 >> Washington University School of Medicine Saint Louis, Missouri, United States, 63110 收起 <<
NCT01486940 Diabetes Diab... 展开 >>etes Mellitus, Type 1 收起 << Phase 3 Completed - -
NCT01707134 Diabetes Diab... 展开 >>etes Mellitus, Type 1 收起 << Phase 3 Completed - -

Insulin (human) 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

0.17mL

0.03mL

0.02mL

0.86mL

0.17mL

0.09mL

1.72mL

0.34mL

0.17mL

Insulin (human) 技术信息

CAS号11061-68-0
分子式C257H383N65O77S6
分子量 5807.57
别名 胰岛素(人) ;Insulin regular;Insulin
运输蓝冰
存储条件

液体 -20°C:3-6个月-80°C:12个月

粉末 Sealed in dry,Store in freezer, under -20°C

溶解度

H2O: 10 mg/mL(1.72 mM),配合低频超声,并调节pH至2

动物实验配方
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