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Herbacetin {[allProObj[0].p_purity_real_show]}

货号:A305232 同义名: Isoarticulatidin;3,5,7,8,4'-Pentahydroxyflavone

Herbacetin, a natural product isolated and purified from the herbs of Equisetum hyemale L. It was found to efficiently block the enzymatic activity of SARS-CoV 3CLpro.

HazMat Fee +

There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Herbacetin 化学结构 CAS号:527-95-7
Herbacetin 化学结构
CAS号:527-95-7
Herbacetin 3D分子结构
CAS号:527-95-7
Herbacetin 化学结构 CAS号:527-95-7
Herbacetin 3D分子结构 CAS号:527-95-7
规格 价格 会员价 库存 数量
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Herbacetin 纯度/质量文件 产品仅供科研

货号:A305232 标准纯度: {[allProObj[0].p_purity_real_show]}
批次查询: 批次纯度:

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Herbacetin 生物活性

描述 Herbacetin, a natural product isolated and purified from the herbs of Equisetum hyemale L., induces HepG2 apoptosis in a ROS-mediated mitochondria-dependent manner that correlate with the inactivation of the PI3K/Akt pathway, exerts an anti-inflammatory effect through suppression of LPS-induced JNK and NF-κB signaling pathways and diminished production of proinflammatory cytokines and mediators, and is a Met inhibitor with a potential utility in cancer therapeutics, suppresses the HGF-induced motility of human breast cancer MDA-MB-231 cells by inhibiting c-Met and Akt phosphorylation.
4. Herbacetin

Herbacetin 参考文献

[1]Li L, Sapkota M, et al. Herbacetin inhibits inducible nitric oxide synthase via JNK and nuclear factor-κB in LPS-stimulated RAW264.7 cells. Eur J Pharmacol. 2015 Oct 15;765:115-23.

[2]Hyuga S, Hyuga M, et al. Herbacetin, a constituent of ephedrae herba, suppresses the HGF-induced motility of human breast cancer MDA-MB-231 cells by inhibiting c-Met and Akt phosphorylation. Planta Med. 2013 Nov;79(16):1525-30.

Herbacetin 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.31mL

0.66mL

0.33mL

16.54mL

3.31mL

1.65mL

33.09mL

6.62mL

3.31mL

Herbacetin 技术信息

CAS号527-95-7
分子式C15H10O7
分子量 302.236
别名 Isoarticulatidin;3,5,7,8,4'-Pentahydroxyflavone;8-hydroxy Kaempferol
运输蓝冰
存储条件

液体 -20°C:3-6个月-80°C:12个月

粉末 Sealed in dry,2-8°C

溶解度

DMSO: 105 mg/mL(347.41 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方
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