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货号 产品名 纯度
A2417353 现货 LMTK3-IN-1

LMTK3-IN-1是一种 ATP 竞争性 LMTK3 抑制剂,能通过泛素蛋白酶体途径降解 LMTK3,在乳腺癌细胞系中展现出抗癌活性,适用于癌症研究。

98%
A1219210 现货 BAY-474

BAY 474 is a tyrosine-protein kinase c-Met inhibitor and a structural genomics consortium (SGC) epigenetics probe.

99%+
A1229396 现货 c-Met-IN-15

c-Met-IN-15是一种c-Met激酶抑制剂。

99%+
A1229788 现货 SU 5616

SU 5616是一种有机化合物,可能通过调控酪氨酸激酶信号转导来影响细胞增殖。它在癌症和细胞生物学研究中具有潜力。

99%+
A1942329 现货 Zongertinib

Zongertinib是一种有效的 HER2EGFR 酪氨酸激酶抑制剂,IC50 分别为 13 nM 和 579 nM。该化合物展现出显著的抗肿瘤活性,特别适用于多种实体瘤的研究,具有潜在的癌症治疗应用。

98%
A1598762 现货 C-Met inhibitor D9

C-Met inhibitor D9是一种选择性的c-Met抑制剂,用于调节细胞增殖和迁移,主要用于研究癌症和其他疾病的治疗。

95%
A1942376 现货 Risvodetinib

Risvodetinib是一种高效的蛋白酪氨酸激酶抑制剂,主要通过抑制 Abelson 家族激酶(如 c-Abl1、c-Abl2 和 c-kit)的活性,具有用于白血病等癌症研究的潜力。

98%
A1176772 现货 Elzovantinib

Elzovantinib是一种 SRC、MET 和 c-FMS 的抑制剂,具有抗癌和治疗各种癌症的潜力。

98+%
A1212551 现货 SYN1143

c-Met/RON Dual Kinase Inhibitor is a potent inhibitor against the kinase activities of HGF receptor c-Met and MSP (Macrophage Stimulating Protein) receptor RON with IC50 of 4 and 9 nM, respectively, and it is reported to inhibit NIH3T3 TRP-Met and U-87 tumor growth in mice in vivo in a dose-dependent manner.

99%+
A275907 现货 JNJ-38877605

JNJ-38877605 is an ATP-competitive inhibitor of c-Met with IC50 of 4 nM.

98+%
A147035 现货 MK-8033 HCl

MK8033 HCl is a specific dual ATP competitive c-Met/Ron inhibitor (IC50=1 nM Wt c-Met) under investigation as a treatment for cancer.

98%
A263510 现货 SGX-523

SGX-523 is a potent and selective c-Met inhibitor with IC50 of 4 nM.

99%+
A103152 现货 AMG-337

AMG-337 is a potent, highly selective and ATP-competitive MET kinase inhibitor with an IC50 of < 5nM in enzymatic assays.

99%+
A1002083 现货 Bozitinib

Bozitinib (PLB-1001) is a highly selective c-MET kinase inhibitor with blood-brain barrier permeability. Bozitinib (PLB-1001) is a ATP-competitive small-molecule inhibitor, binds to the conventional ATP-binding pocket of the tyrosine kinase superfamily[1].

98%+
A334110 现货 SAR125844

SAR125844 is a potent and highly selective c-Met inhibitor with potential antineoplastic activity.

98%+
A193720 现货 Capmatinib/卡马替尼

INCB28060 is a potent and selective c-MET kinase inhibitor. INCB28060 inhibits c-MET kinase activity with an average IC50 of 0.13 nM.

99%+
A248902 现货 c-Met inhibitor 1

c-Met Inhibitor 1 is a c-Met receptor signaling pathway inhibitor, used for the treatment of cancer including gastric, glioblastoma, and pancreatic cancer.

99%+
A670353 现货 PF-04217903

PF-04217903 is a selective ATP-competitive c-Met inhibitor with IC50 of 4.8 nM, susceptible to oncogenic mutations (no activity to Y1230C mutant).

99%+
A569590 现货 Savolitinib/赛沃替尼

Savolitinib is an orally bioavailable inhibitor of the c-Met receptor tyrosine kinase (IC50= 5 nM) with potential antineoplastic activity.

98%
A242274 现货 Tepotinib/特泊替尼

EMD 1214063 is a potent and selective c-Met inhibitor with IC50 of 4 nM, > 200-fold selective for c-Met than IRAK4, TrkA, Axl, IRAK1, and Mer.

99%+
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