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Fumaric acid

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Chemical Structure| 110-17-8 同义名 : 2-Butenedioic acid;Trans-Butenedioic acid;Tumaric acid;Kyselina fumarova;Fumarate;Lichenic acid;Donitic acid;Boletic acid;Allomaleic acid
CAS号 : 110-17-8
货号 : A145318
分子式 : C4H4O4
纯度 : 99+%
分子量 : 116.072
MDL号 : MFCD00002700
存储条件：

粉末 Sealed in dry,Room Temperature

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 25 mg/mL(215.38 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

H2O: 10 mg/mL(86.15 mM)，配合低频超声助溶
动物实验配方：
生物活性
描述 Fumaric acid (FA), a metabolic intermediate, has been identified as an important carbohydrate derived platform chemical. Fumaric acid as a four-carbon unsaturated dicarboxylic acid is widely used in the food and chemical industries[1]. Fumaric acid is a naturally occurring organic acid that is an intermediate of the tricarboxylic acid cycle. Fungal species belonging to Rhizopus have traditionally been employed for the production of fumaric acid[2]. Fumaric acid concentrations increase with plant age and light intensity in Arabidopsis leaves. Moreover, Arabidopsis phloem exudates contain significant quantities of fumaric acid, raising the possibility that fumaric acid may function in carbon transport[3].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

8.62mL

1.72mL

0.86mL

43.08mL

8.62mL

4.31mL

86.15mL

17.23mL

8.62mL
参考文献

[1]Liu H, Ma J, Wang M, Wang W, Deng L, Nie K, Yue X, Wang F, Tan T. Food Waste Fermentation to Fumaric Acid by Rhizopus arrhizus RH7-13. Appl Biochem Biotechnol. 2016 Dec;180(8):1524-1533

[2]Song CW, Kim DI, Choi S, Jang JW, Lee SY. Metabolic engineering of Escherichia coli for the production of fumaric acid. Biotechnol Bioeng. 2013 Jul;110(7):2025-34

[3]Chia DW, Yoder TJ, Reiter WD, Gibson SI. Fumaric acid: an overlooked form of fixed carbon in Arabidopsis and other plant species. Planta. 2000 Oct;211(5):743-51