烟曲霉素 /Fumagillin
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货号：A859732
同义名：
Amebacilin;NSC9168
Fumagillin is a complex biomolecule and used as an antimicrobial agent.
Fumagillin 化学结构
Fumagillin 3D分子结构
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Fumagillin 纯度/质量文件 产品仅供科研
货号：A859732
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Fumagillin 质控信息
Fumagillin 生物活性
描述
Fumagillin is an active amebicide and anti-infective isolated from the fungus Aspergillus fumigatus[3] [4] [5] [6]
Fumagillin 参考文献
[1] Watanabe N, Nishihara Y, et al. Fumagillin suppresses HIV-1 infection of macrophages through the inhibition of Vpr activity. FEBS Lett. 2006 May 15;580(11):2598-602.
[2] Sin N, Meng L, Wang MQ, et al. The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2. Proc Natl Acad Sci U S A. 1997 Jun 10;94(12):6099-103.
[3] Lefkove B, Govindarajan B, Arbiser JL. Fumagillin: an anti-infective as a parent molecule for novel angiogenesis inhibitors. Expert Rev Anti Infect Ther. 2007 Aug;5(4):573-9
[4] An J, Wang L, Patnode ML, Ridaura VK, Haldeman JM, Stevens RD, Ilkayeva O, Bain JR, Muehlbauer MJ, Glynn EL, Thomas S, Muoio D, Summers SA, Vath JE, Hughes TE, Gordon JI, Newgard CB. Physiological mechanisms of sustained fumagillin-induced weight loss. JCI Insight. 2018 Mar 8;3(5):e99453
[5] Guruceaga X, Perez-Cuesta U, Pellon A, Cendon-Sanchez S, Pelegri-Martinez E, Gonzalez O, Hernando FL, Mayayo E, Anguita J, Alonso RM, Keller NP, Ramirez-Garcia A, Rementeria A. Aspergillus fumigatus Fumagillin Contributes to Host Cell Damage. J Fungi (Basel). 2021 Nov 3;7(11):936
[6] Zbidah M, Lupescu A, Jilani K, Lang F. Stimulation of suicidal erythrocyte death by fumagillin. Basic Clin Pharmacol Toxicol. 2013 May;112(5):346-51
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Fumagillin 实验方案
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摩尔计算器
总药量计算器
工作液计算器
存储液制备
1mg
5mg
10mg
1 mM
5 mM
10 mM
2.18mL
0.44mL
0.22mL
10.90mL
2.18mL
1.09mL
21.81mL
4.36mL
2.18mL
Fumagillin 技术信息
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