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Fluralaner

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Chemical Structure| 864731-61-3 同义名 : A1443;AH252723;Fluralaner, trade name: Bravecto.
CAS号 : 864731-61-3
货号 : A724974
分子式 : C22H17Cl2F6N3O3
纯度 : 98%
分子量 : 556.285
MDL号 : MFCD30533410
存储条件：

粉末 Sealed in dry,2-8°C

液体 -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 190 mg/mL(341.55 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Fluralaner (INN) is a systemic insecticide and acaricide Fluralaner through potent blockage of GABA and L-glutamate gated chloride channels.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.80mL

0.36mL

0.18mL

8.99mL

1.80mL

0.90mL

17.98mL

3.60mL

1.80mL
参考文献

[1]Williams H, et al. Fluralaner, a novel isoxazoline, prevents flea (Ctenocephalides felis) reproduction in vitro and in asimulated home environment. Parasit Vectors. 2014 Jun 19;7:275.

[2]Walther FM, et al. Safety of fluralaner, a novel systemic antiparasitic drug, in MDR1(-/-) Collies after oral administration. Parasit Vectors. 2014 Mar 6;7:86.