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尼泊金乙酯 /Ethylparaben {[allProObj[0].p_purity_real_show]}

货号:A569752 同义名: 羟苯乙酯 / Ethyl parahydroxybenzoate;Ethyl 4-hydroxybenzoate

Ethylparaben, a natural product isolated and purified from the male melon fly Dacus cucurbitae, is the ethyl ester of p-hydroxybenzoic acid, used as an antifungal preservative.

Ethylparaben 化学结构 CAS号:120-47-8
Ethylparaben 化学结构
CAS号:120-47-8
Ethylparaben 3D分子结构
CAS号:120-47-8
Ethylparaben 化学结构 CAS号:120-47-8
Ethylparaben 3D分子结构 CAS号:120-47-8
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Ethylparaben 纯度/质量文件 产品仅供科研

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Ethylparaben 生物活性

描述 Ethylparaben (EP), a kind of parabens, has been widely used as a cosmetic and food preservative [1] . Although EP, as a preservative, had been thought to be safe for humans, some studies showed that it has estrogenic effects and may cause some estrogenicity-related diseases [1-2] . In vitro studies, EP could significantly stimulate the proliferation of MCF-7 cells at a higher concentration than 17beta-estradiol [3] . In vivo studies, it was found that 0.02% EP could enhance the fertility of fruit flies, while at a higher concentration, more than 0.10%, EP could suppress the fruit flies' survivability [1] . Besides these, EP also could increase the incidence of breast cancer in rats [2] .

Ethylparaben 参考文献

[1]Liu T, Li Y, et al. Ethylparaben affects lifespan, fecundity, and the expression levels of ERR, EcR and YPR in Drosophila melanogaster. J Insect Physiol. 2014.

[2]Sun L, Yu T, et al. The estrogenicity of methylparaben and ethylparaben at doses close to the acceptable daily intake in immature Sprague-Dawley rats. Sci Rep. 2016.

[3]Okubo T, Yokoyama Y, et al. ER-dependent estrogenic activity of parabens assessed by proliferation of human breast cancer MCF-7 cells and expression of ERalpha and PR. Food Chem Toxicol. 2001;39(12):1225-32.

Ethylparaben 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

6.02mL

1.20mL

0.60mL

30.09mL

6.02mL

3.01mL

60.18mL

12.04mL

6.02mL

Ethylparaben 技术信息

CAS号120-47-8
分子式C9H10O3
分子量 166.174
别名 羟苯乙酯 ;Ethyl parahydroxybenzoate;Ethyl 4-hydroxybenzoate;NSC 23514
运输蓝冰
存储条件

液体 -20°C:3-6个月-80°C:12个月

粉末 Sealed in dry,Room Temperature

溶解度

DMSO: 105 mg/mL(631.87 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方
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