Bikinin
99%+
货号：A176791
同义名：
Abrasin
Bikinin acts as an ATP-competitive inhibitor of arabidopsis GSK-3 and effective activator of brassinosteroid (BR) signaling.
Bikinin 化学结构
Bikinin 3D分子结构
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Bikinin 纯度/质量文件 产品仅供科研
货号：A176791
标准纯度：
99%+
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Bikinin 质控信息
Bikinin 生物活性
靶点
描述
Bikinin is a non-steroidal, ATP-competitive inhibitor of plant GSK-3(Glycogen synthase kinase 3)/Shaggy-like kinases and activates BR (brassinosteroids) signaling. Bikinin reduces transcript levels of NbRBOHB and BR-induced NbRBOHB expression in TRV:00, TRV:NbDWARF, TRV:NbBRI1, TRV:NbBSK1, TRV:NbBAK1, TRV:NbBIK1 and TRV:NbBSU1 plants. Bikinin largely inhibits BR-increased ROS accumulation[3] [4] [5]
Bikinin 参考文献
[1] Cai Z, Liu J, et al. GSK3-like kinases positively modulate abscisic acid signaling through phosphorylating subgroup III SnRK2s in Arabidopsis. Proc Natl Acad Sci U S A. 2014 Jul 1;111(26):9651-6.
[2] De Rybel B, Audenaert D, et al. Chemical inhibition of a subset of Arabidopsis thaliana GSK3-like kinases activates brassinosteroid signaling. Chem Biol. 2009 Jun 26;16(6):594-604.
[3] Deng XG, Zhu T, Peng XJ, Xi DH, Guo H, Yin Y, Zhang DW, Lin HH. Role of brassinosteroid signaling in modulating Tobacco mosaic virus resistance in Nicotiana benthamiana. Sci Rep. 2016 Feb 3;6:20579
[4] De Rybel B, Audenaert D, Vert G, Rozhon W, Mayerhofer J, Peelman F, Coutuer S, Denayer T, Jansen L, Nguyen L, Vanhoutte I, Beemster GT, Vleminckx K, Jonak C, Chory J, Inzé D, Russinova E, Beeckman T. Chemical inhibition of a subset of Arabidopsis thaliana GSK3-like kinases activates brassinosteroid signaling. Chem Biol. 2009 Jun 26;16(6):594-604
[5] Cai Z, Liu J, Wang H, Yang C, Chen Y, Li Y, Pan S, Dong R, Tang G, Barajas-Lopez Jde D, Fujii H, Wang X. GSK3-like kinases positively modulate abscisic acid signaling through phosphorylating subgroup III SnRK2s in Arabidopsis. Proc Natl Acad Sci U S A. 2014 Jul 1;111(26):9651-6
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Bikinin 实验方案
计算器
摩尔计算器
总药量计算器
工作液计算器
存储液制备
1mg
5mg
10mg
1 mM
5 mM
10 mM
3.66mL
0.73mL
0.37mL
18.31mL
3.66mL
1.83mL
36.62mL
7.32mL
3.66mL
Bikinin 技术信息
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