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Bax inhibitor peptide V5
Bax inhibitor peptide V5
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货号：A879691
同义名：
BAX Inhibiting Peptide V5;BIP-V5
Bax inhibitor pe ptBax 介导的凋亡 抑制剂。
Bax inhibitor peptide V5 化学结构
Bax inhibitor peptide V5 3D分子结构
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Bax inhibitor peptide V5 纯度/质量文件 产品仅供科研
货号：A879691
标准纯度：
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产品说明书
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Bax inhibitor peptide V5 质控信息
Bax inhibitor peptide V5 生物活性
描述
Bax inhibitor peptide V5 (BIP-V5) is a Bax-mediated apoptosis inhibitor that inhibits a wide range of caspases. Treatment of mouse islets with BIP-V5 (100 μmol/L) upregulated the expressions of anti-apoptotic proteins Bcl-2 and X-linked inhibitor of apoptosis protein by more than 3- and 11-fold, respectively, and downregulated the expressions of Bax, Bad, and nuclear factor-κB-p65 by 10, 30, and nearly 50%, respectively[3] [4] [3]
Bax inhibitor peptide V5 参考文献
[1] Jo MJ, Paek AR, et al. Regulation of cancer cell death by a novel compound, C604, in a c-Myc-overexpressing cellular environment. Eur J Pharmacol. 2015 Dec 15;769:257-65.
[2] Rivas-Carrillo JD, Soto-Gutierrez A, et al. Cell-permeable pentapeptide V5 inhibits apoptosis and enhances insulin secretion, allowing experimental single-donor islet transplantation in mice. Diabetes. 2007 May;56(5):1259-67.
[3] Rivas-Carrillo JD, Soto-Gutierrez A, Navarro-Alvarez N, et al. Cell-permeable pentapeptide V5 inhibits apoptosis and enhances insulin secretion, allowing experimental single-donor islet transplantation in mice. Diabetes. 2007;56(5):1259-1267.
[4] Jo MJ, Paek AR, Choi JS, et al. Regulation of cancer cell death by a novel compound, C604, in a c-Myc-overexpressing cellular environment. Eur J Pharmacol. 2015;769:257-265.
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Bax inhibitor peptide V5 实验方案
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1mg
5mg
10mg
1 mM
5 mM
10 mM
1.70mL
0.34mL
0.17mL
8.52mL
1.70mL
0.85mL
17.04mL
3.41mL
1.70mL
Bax inhibitor peptide V5 技术信息
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