货号：A125426同义名：
阿米卡星硫酸盐
/ BAY 41-6551 disulfate;BB-K8
Amikacin Disulfateis is an antibiotic used for a number of bacterial infections, including joint infections, intra-abdominal infections, meningitis, pneumonia, sepsis, and urinary tract infections, and treatment of multidrug-resistant tuberculosis.
Amikacin (disulfate), a semisynthetic analog of kanamycin, is very active against most gram-negative bacteria including gentamicin- and tobramycin-resistant strains. High response rates have been reported with the use of amikacin combined with beta-lactam antibiotics in immunocompromised or granulocytopenic patients[3]. Amikacin is useful against gentamicin-resistant gram-negative bacilli and also in the treatment of infections caused by susceptible Nocardia and nontuberculous mycobacteria[4]. Moreover, amikacin 20 mg/kg once daily provided a higher probability of target attainment with lower toxicity than dosing three times daily[5].
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