7-Amino-4-methylcoumarin is a natural product isolated and purified from an endophytic Xylaria fungal species and exhibited strong antibacterial and antifungal activities in vitro against Aspergillus, Candida, Escherichia, Staphylococcus, Salmonella and Vibrio species, among others. It is also a reagent employed in the preparation of fluorogenic AMC-based substrates for the detection of proteolytic enzyme activity. AMC has been utilized as a fluorescent probe to analyze glycoproteins' monosaccharides and N-linked oligosaccharides via chromatography and has been used as a laser dye.
7-Amino-4-methylcoumarin, a member of the coumarin family, is derived from the endophytic fungus Xylaria sp. and exhibits broad antimicrobial activity. It is widely used as a laser dye emitting blue light, and as a fluorescent probe for analyzing glycoproteins’ monosaccharides and N-linked oligosaccharides, with excitation and emission wavelengths of 351 nm and 430 nm, respectively. This compound's versatility extends its use in scientific research, particularly in the fields of microbiology and bioanalytical chemistry[1].
搜索
