AZD5904 is a potent and irreversible MPO inhibitor with IC50 value of 140nM. Continuous subcutaneous AZD5904 infusion during the 2 week selectively blocked HFD (high-fat diet)'s microvascular effect.

MPO-IN-28 is a MPO inhibitor with IC50 value of 44nM.

PF-1355 is a selective 2-thiouracil mechanism-based MPO inhibitor, used for treatment of vasculitic diseases.

Verdiperstat is a potent, reversible and orally active myeloperoxidase (MPO) selective inhibitor with IC50 of 630 nM.

PF-06282999 is a potent and selective myeloperoxidase inhibitor which is potential useful for the treatment of cardiovascular diseases.