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全部(44) Inducer(1) Inhibitor(9)
L-Chicoric acid, a natural product isolated and purified from the herbs of Echinacea purpurea, is an inhibitor of human immunodeficiency virus type 1 (HIV-1) integrase in vitro and of HIV-1 replication in tissue culture.
Raltegravir是一种强力的整合酶(IN)抑制剂,用于治疗HIV感染。
Dolutegravir sodium (S/GSK1349572 sodium)是一种高效且口服生物利用度良好的HIV整合酶链转移抑制剂,其对HIV-1整合酶催化的链转移的IC50为2.7 nM。它在外周血单个核细胞中抑制HIV-1病毒复制的IC50为0.51 nM,并且对HIV-1 Y143R、N155H和G140S/Q148H突变体保持高效能(EC50 = 3.6-5.8 nM)。
Dolutegravir (S/GSK1349572) 是一种高效且口服活性的 HIV 整合酶链转移抑制剂,对 HIV-1 整合酶催化的链转移的 IC50 为 2.7 nM。Dolutegravir (S/GSK1349572) 在外周血单核细胞中抑制 HIV-1 病毒复制的 IC50 为 0.51 nM,并且对 HIV-1 Y143R、N155H 和 G140S/Q148H 突变体保持高效 (EC50 = 3.6-5.8 nM)。
Raltegravir potassium(MK 0518)是一种用于治疗HIV感染的强力整合酶(IN)抑制剂。
Elvitegravir is a quinolinemonocarboxylic-acid HIV-1 integrase strand transfer inhibitor used to treat HIV infection. It is also a cytochrome P450 2C9 inducer.
Cabotegravir is a potent HIV integrase inhibitor as an oral lead-in tablet and long-acting injectable for the treatment and prevention of HIV infection. Cabotegravir is an inhibitor of OAT1 (IC50 0.81 μM) and OAT3 (IC50 0.41 μM).
Bictegravir is a potent, unboosted, once-Daily HIV-1 Integrase Strand Transfer inhibitor (INSTI) (IC50 - 1.6 nM) with improved pharmacokinetics and in vitro resistance profile.
HIV-1 integrase inhibitor 8 is a HIV-1 integrase inhibitor, compound 8.
Cichoric Acid is a naturally occuring phenylpropanoid found in a variety of plants, used as an HIV Integrase inhibitor.
7-Amino-4-methyl-3-coumarinylacetic acid (AMCA) is fluorescent protein labeling agent.1 It contains an N-hydroxysuccinimide ester that reacts with lysine residues to form photostable amide links. Upon activation with UV light, AMCA displays emission maxima of 400-460 nm. It has commonly been used in multiplex immunophenotyping applications.
Tags: HIV整合酶 | HIV Integrase | 抗感染 | Anti-infection | HIV整合酶 相关产品
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