4E2RCat is an inhibitor of eIF4E-eIF4G interaction with an IC50 of 13.5 μM.

4E1RCat blocks interaction between eIF4E:eIF4G and eIF4E:4E-BP1, prevents assembly of the eIF4F complex and inhibits cap-dependent translation with IC50 ~4 μM.

4EGI-1 是一种 eIF4E/eIF4G 相互作用的破坏剂，对 eIF4E 的结合解离常数 (Kd) 为 25 μM。

Briciclib is a small molecule that suppresses cyclin D1 accumulation in cancer cells.

GCN2iB是一种ATP竞争性的丝氨酸/苏氨酸蛋白激酶GCN2抑制剂，IC50为2.4 nM。

SBI-0640756是一种 eIF4G1 抑制剂，能够有效破坏 eIF4F 复合体。它在抑制癌细胞增殖和研究翻译调控方面具有潜在的应用价值。

GCN2-IN-1 is a potent general control nonderepressible 2 kinase (GCN2) inhibitor with IC50s of <0.3 μM in the enzyme and cell assay.