Chlorprothixene is an antagonist of multiple receptors including 5-HT2 (Ki = 3.4 nM), D1 (Ki = 18 nM), D2 (Ki = 18 nM), D3 (Ki = 4.56 nM), H1 (Ki = 3.75 nM), muscarinic acetylcholine receptors, α1-Adrenergic.

Pimethixene maleate是一种抗组胺药物，主要用于过敏性疾病的研究。它通过阻断 H1 受体，对过敏反应有显著的抑制作用。

SCH 23390 HCl is an antagonist of dopamine receptor D1 and D5 with Ki of 0.2 nM and 0.3 nM, respectively.

Rotundine is antagonist for domapmine D1 receptor(Ki = 124 nM) and has a lower binding activity of domapmine D2 receptor and domapmine D3 receptor. It can also inhibit 5-HT1A (Ki = 340 nM).

Loxapine succinate salt is an multiple-target antagonist of both D2/D4 dopamine receptor and 5-HT2A/2B, 5-H7 serotonin receptor, used as an antipsychotic agent.

Ansofaxine HCl is a multiple-target reuptake inhibitor with IC50 values of 723nM, 491nM and 763nM for serotonin, dopamine and norepinephrine reuptake.

Pimozide is a dopamine receptor antagonist, with Kis of 1.4 nM, 2.5 nM and 588 nM for dopamine D2, D3 and D1 receptors, respectively, and also has affinity at α1-adrenoceptor, with a Ki of 39 nM; also inhibits STAT3 and STAT5.

Penfluridol, a T-type calcium channel blocker, is a highly potent, first generation diphenylbutylpiperidine antipsychotic.