Hydroxysafflor yellow A is a flavonoid derived and isolated from traditional Chinese medicine Carthamus tinctorius L., possessing anti-tumor activity.

Crocin, a natural product isolated and purified from the stigma of Crocus sativus L., can relax smooth muscles with a great potential to be a candidate for the treatment of asthma, protect liver and skeletal muscle tissue against exercise-induced oxidative damage by preventing reactive oxygen species (ROS) production, improve toxic effects of DZN via reducing lipid peroxidation and restoring altered contractile and relaxant responses in rat aorta, protect rat gastric mucosa against ethanol-induced injury via anti-inflammatory, anti-oxidative, anti-apoptotic and mucin-secretagogue mechanisms that are probably mediated by enhanced PGE2 release, significantly inhibit the growth of HO-8910 cells and arrest them in the G0/G1 phase, and also promote ovarian cancer HO-8910 cell apoptosis, most likely by increasing p53 and Fas/APO-1 expression, and then activating the apoptotic pathway regulated by Caspase-3.

Picrocrocin 是从藏红花中提取的类胡萝卜素。它具有抗癌活性，并抑制 SKMEL-2 人恶性黑色素瘤细胞的生长。

Crocetin, a saffron derivative, is an inhibitor of human lactate dehydrogenase 5 in the antiglycolytic approach against cancer.

Trans-crocetin sodium, also known as Transcrocetinate sodium or Sodium crocetinate, is potentially for the treatment of glioblastoma. Trans-crocetin improves amyloid-β degradation in monocytes from Alzheimer's Disease patients. trans-crocetin inhibit glutamatergic synaptic transmission in rat cortical brain slices. Crocetin inhibits invasiveness of MDA-MB-231 breast cancer cells via downregulation of matrix metalloproteinases.

Crocin, a natural product with anti-inflammatory, antihyperlipidemic, antidepressant and anti-apoptotic effects, can ameliorate CCl4-induced liver injury via inhibition of inflammatory cytokines, caspase3 and oxidative stress along with modulation of liver metabolizing enzymes favoring elimination of CCl4 toxic metabolite, it's isolated and purified from the stigma of Crocus sativus L..