Calhex 231 HCl是一种通过负变构调节抑制钙敏感受体 (CaSR) 的化合物，能够阻断 Ca2+ 诱导的肌醇磷酸酯积累，IC₅₀ 为 0.39 μM。该化合物广泛用于糖尿病性心肌病 (DCM) 及其他钙调节相关疾病的研究。

Calindol hydrochloride是一种拟钙钙敏感受体 (CaSR) 的正变构调节剂，EC₅₀ 为 132 nM，适用于研究钙离子信号传导和代谢调节途径，特别是在钙敏感受体介导的疾病研究中具有广泛应用。

AC-265347是一种钙敏感受体（CaSR）激动剂和正向变构调节剂（ago-PAM），功能亲和力（pKB）为5.1。AC-265347可用于甲状旁腺功能亢进及相关疾病的研究。

Evocalcet是一种口服活性的钙敏感受体 (CaSR) 激动剂，能有效抑制甲状旁腺激素 (PTH) 的分泌。它适用于甲状旁腺功能亢进的研究和治疗。

Etelcalcetide HCl is the HCl salt of etelcalcetide is a calcium-sensing receptor agonist for the treatment of secondary hyperparathyroidism for patients with chronic kidney disease (CKD) on hemodialysis.

NPS-2143 HCl (SB-262470A hydrochloride)是一种口服活性的钙感受器拮抗剂，选择性且高效地拮抗钙离子感受器（CaSR）。NPS-2143盐酸盐（SB-262470A盐酸盐）能够阻断在表达人体钙感受器的HEK 293细胞中通过激活钙离子受体引起的细胞内Ca2+浓度增加（IC50=43 nM）。

Tecalcet Hydrochloride, an orally active calcimimetic compound, allosterically and positively modulates the calcium-sensing receptor (CaSR). Tecalcet Hydrochloride increases the sensitivity to activation by extracellular Ca2+.

Cinacalcet（AMG 073）是一种口服活性、别构激动剂的钙受体（CaR），用于心血管疾病研究。

Cinacalcet hydrochloride (AMG-073 hydrochloride)是一种口服活性、别构激动剂Ca受体（CaR），用于治疗心血管疾病。

Stretch-activated calcium channel blocker; calcium-sensing receptor agonist

Strontium ranelate stimulates the calcium sensing receptors (CaSR) and leads to the differentiation of pre-osteoblast to osteoblast which increases the bone formation.

Ligustroflavone, extracted from Ligustrum lucidum, is a potential candidate as calcium-sensing receptor (CaSR) antagonist. Ligustroflavone exhibits protective effects against diabetic osteoporosis in mice[1].

Etelcalcetide is a calcium-sensing receptor agonist for the treatment of secondary hyperparathyroidism for patients with chronic kidney disease (CKD) on hemodialysis.

SB-423562 is a short-acting calcium-sensing receptor (CaR) antagonist.