EN4是一种针对MYC的半胱氨酸171 (C171) 的共价配体，具有高选择性和抗肿瘤作用。它有效下调MYC靶标，在癌症研究中具有重要应用。

MYCi975 improved analog of MYCi361 which is a MYC inhibitor. It showed better tolerability compared with MYCi361.

KJ Pyr 9 is a small-molecule inhibitor of MYC. The Kd of KJ Pyr 9 for MYC in vitro is 6.5±1.0 nM, as determined by backscattering interferometry.

MYCi361 is a MYC inhibitor with Kd value of 3.2μM. It engages MYC inside cells, disrupts MYC/MAX dimers, and impairs MYC-driven gene expression. MYCi361 suppressed in vivo tumor growth in mice, increased tumor immune cell infiltration, upregulated PD-L1 on tumors, and sensitized tumors to anti-PD1 immunotherapy.

10074-A4是一种 c-Myc 抑制剂，能够与 c-Myc370-409 在不同位点结合，具有抗癌活性。

Mycro3 is a small-molecule inhibitor of Myc-Max dimerization. The average residual tumor of Pdx1-cre/KRAS* mice after Mycro3 treatment (100mg/kg, orally, daily for 2 months) is approximately 30%.

MYCMI-6 (NSC354961) is a potent and selective endogenous MYC:MAX protein interactions inhibitor. MYCMI-6 blocks MYC-driven transcription and binds selectively to the MYC bHLHZip domain with a Kd of 1.6 μM. MYCMI-6 inhibits tumor cell growth in a MYC-dependent manner (IC50<0.5 μM). MYCMI-6 is not cytotoxic to normal human cells. MYCMI-6 induces apoptosis .

IZCZ-3 是一种有效的 c-MYC 转录抑制剂，具有抗肿瘤活性。

Agrimol B 是一种多酚类化合物，口服有效的 SIRT1 激活剂。它具有抗脂肪生成和抗癌活性，并对植物病原体表现出抗菌特性。

10058-F4是一种 c-Myc 抑制剂，通过阻止 c-Myc-Max 二聚化和靶基因的转录激活，具有用于癌症治疗研究的潜力。

ML327 is a blocker of MYC which can also de-repress E-cadherin transcription and reverse Epithelial-to-Mesenchymal Transition (EMT).

10074-G5 is a c-Myc Max interaction inhibitor.