Alprostadil is an analog of prostaglandin which is prostaglandin E1 agonist with vasodilatory properties and can be used to treat erectile dysfunction.

Bimatoprost, a analog of prostaglandin, can control the progression of glaucoma and ocular hypertension.

Lubiprostone is an ClC-2 chloride channel activator used in the treatment of idiopathic chronic constipation.

Latanoprost is a prostaglandin F2alpha analogue and a prostanoid selective FP receptor agonist with an ocular hypertensive effect. Latanoprost increases uveoscleral outflow and thereby reduces intraocular pressure.

Prostaglandin E2 is a natural prostaglandin and acts as a vasodilator by activating the prostaglandin E2 receptor.