Lubiprostone is an ClC-2 chloride channel activator used in the treatment of idiopathic chronic constipation.

Alprostadil is an analog of prostaglandin which is prostaglandin E1 agonist with vasodilatory properties and can be used to treat erectile dysfunction.

Latanoprost is a prostaglandin F2alpha analogue and a prostanoid selective FP receptor agonist with an ocular hypertensive effect. Latanoprost increases uveoscleral outflow and thereby reduces intraocular pressure.

Bimatoprost, a analog of prostaglandin, can control the progression of glaucoma and ocular hypertension.

Prostaglandin E2 is a natural prostaglandin and acts as a vasodilator by activating the prostaglandin E2 receptor.