PD180970是 一种高度有效且 ATP 竞争性的 p210Bcr-Abl 激酶抑制剂，抑制 p210Bcr-Abl 自磷酸化的 IC50 为 5 nM。

GDP366 is a dual inhibitor of survivin and Op18.

YM155 is an inhibitor of survivin with IC50 of 0.54 nM.

LQZ-7I is a survivin inhibitor through inhibition of survivin dimerization. It effectively inhibited xenograft tumor growth and induced survivin loss in tumor when given orally.

FL118是一种口服有效的Survivin抑制剂，通过结合DDX5（p68）蛋白并诱导其去磷酸化与降解，展示了在癌症治疗中的潜力，主要用于肿瘤细胞增殖和存活机制的研究。

Isolinderalactone通过抑制内皮细胞 VEGFR2 活化，抑制人胶质母细胞瘤的生长和血管生成，同时抑制 Bcl-2、survivin 和 XIAP 的表达，并增加 cleaved caspase-3 水平。

Cucurbitacin IIa is a triterpene isolated from Hemsleya amalils Diels, induces apoptosis of cancer cells, reduces expression of survivin, reduces phospho-Histone H3 and increases cleaved PARP in cancer cells[1].

YM155 HCl is a potent survivin suppressant by inhibiting Survivin promoter activity with IC50 of 0.54 nM.