Darutoside is a diterpenoid isolated from Siegesbeckia.

Kirenol is a naturall occuring diterpenoid found in S. orientalis, which possess anti-oxidant, anti-inflammatory, anti-allergic, anti-adipogenic, and anti-arthritic activities.

Grandifloric acid is a natural product isolated and purified from the herbs of Siegesbeckia orientalis L..

Darutigenol, a natural product isolated and purified from the herb of Siegesbeckia orientalis., has obvious antithrombotic effect, its mechanism may be related to inhibition of platelet aggregation and adhesion.