PKM2 activator 5是一种 PKM2 激活剂，AC50 值为 0.316 µM，具有改变癌细胞异常代谢的潜力。

PKM2 activator 2是一种抗增殖的丙酮酸激酶 M2 (PKM2) 激活剂，AC50 为 66 nM。PKM2 activator 2通过激活 PKM2，可缓解 Warburg 效应，使细胞恢复正常的糖酵解代谢状态。

TEPP-46 is a potent and selective activator of recombinant pyruvate kinase M2 (PKM2) with half-maximum activating concentration (AC50 value) of 92 nM, and has little or no effect on PKM1, PKL and PKR.

PKR-IN-2 is a pyruvate kinase (PKR) activator with an IC50 of < 100 nM.

PKR-IN-1 is a potent human R-type pyruvate kinase (PKR) inhibitor and also shows potency for mutant PKR including R510Q PKR, R532W PKR, T384W PKR etc.

Etavopivat is a Pyruvate Kinase PKLR activator.

PKR-IN-C16 is a specific protein kinase (PKR) inhibitor. It shows to effectively inhibit RNA-induced PKR autophosphorylation (IC50 = 210 nM) and rescue PKR-dependent translation block (IC50 = 100 nM).

(Rac)-Shikonin是一种天然产物，具有强效的抗肿瘤活性，能够绕过癌症耐药性。

PKM2 activator 4是一种激活PKM2的化合物，适用于与癌症相关的代谢通路研究，展示了在调控癌细胞能量代谢中的重要作用。

D-Fructose-1,6-diphosphate trisodium salt octahydrate is a salt form of D-Fructose-1,6-diphosphate. D-Fructose-1,6-bisphosphate is the precursor of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate in the glycolytic pathway. It is an allosteric activator of enzymes such as pyruvate kinase.

Sodium monofluorophosphate is a competitive inhibitor of pyruvate kinase and alkaline phosphatase with Ki of 3.4 mM and 69 μM, respectively, which also irreversibly inhibits phosphorylase phosphatase with Ki of 0.5 mM.