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描述 | λ-Carrageenan is a seaweed polysaccharide which has been generally used as pro-inflammatory agent in the basic research. λ-Carrageenan is a potent antitumor agent. 6 weeks old mice with high dietary Lambda-Carrageenan consumption showed altered colonic microbiota composition that resulted in degradation of the colonic mucus layer, a raised fecal LPS level, and a decrease in the presence of bacterially derived short-chain fatty acids[1]. λ-Carrageenan (50 mg/kg every two days; intratumoral injection) inhibits tumor growth in B16-F10 and 4T1 bearing mice. λ-carrageenan exhibits considerable antitumor effect via intratumoral injection and significantly improves the tumor immune response with increased infiltrates of immunostimulating cells and increases production of proinflammatory cytokines[2]. |
CAS号 | 9064-57-7 |
分子式 | |
分子量 |
别名 | 角叉胶 |
运输 | 蓝冰 |
存储条件 |
液体 -20°C:3-6个月-80°C:12个月 粉末 Sealed in dry,Room Temperature |
溶解度 |
H2O: 25 mg/mL,配合低频超声助溶 |
动物实验配方 |