产品说明书
λ-Carrageenan
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同义名 : | 角叉胶 |
| CAS号 : | 9064-57-7 | |
| 货号 : | A1147157 | |
| 分子式 : | - | |
| 纯度 : | Viscosity min. 70 mPa-s(0.3 %, H2O, 25 deg-C) | |
| 分子量 : | 0 | |
| MDL号 : | MFCD00151513 | |
| 存储条件： |
粉末 Sealed in dry,Room Temperature 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
H2O: 25 mg/mL，配合低频超声助溶 |
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| 动物实验配方： |
| 生物活性 | |||
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| 描述 | λ-Carrageenan is a seaweed polysaccharide which has been generally used as pro-inflammatory agent in the basic research. λ-Carrageenan is a potent antitumor agent. 6 weeks old mice with high dietary Lambda-Carrageenan consumption showed altered colonic microbiota composition that resulted in degradation of the colonic mucus layer, a raised fecal LPS level, and a decrease in the presence of bacterially derived short-chain fatty acids[1]. λ-Carrageenan (50 mg/kg every two days; intratumoral injection) inhibits tumor growth in B16-F10 and 4T1 bearing mice. λ-carrageenan exhibits considerable antitumor effect via intratumoral injection and significantly improves the tumor immune response with increased infiltrates of immunostimulating cells and increases production of proinflammatory cytokines[2]. | ||
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