Ambeed 大中华区 CN | ZH

中文 - ZH English - EN

Ambeed.cn

搜索

关键字搜索批量搜索

首页 收藏 购物车0
首页 /
抑制剂/激动剂
细胞生物学
/
细胞培养
细胞凋亡 其他抑制剂/激动剂 Hedgehog (Hh)
/
添加剂及辅助试剂
Vitamin 铁死亡抑制剂
/ Vitamin B12

维生素B12 /Vitamin B12 {[allProObj[0].p_purity_real_show]}

货号：A884890 同义名： Cyanocobalamin;Cobalamin

Vitamin B12 is a water-soluble vitamin that is involved in the metabolism of cells as it is a cofactor in DNA synthesis.

Vitamin B12 化学结构 CAS号：68-19-9
Vitamin B12 化学结构
CAS号：68-19-9
Vitamin B12 3D分子结构
CAS号：68-19-9
Vitamin B12 化学结构 CAS号：68-19-9
Vitamin B12 3D分子结构 CAS号：68-19-9
规格 价格 会员价 库存 数量
{[ item.pr_size ]}

{[ getRatePrice(item.pr_rmb, 1,1) ]}

{[ getRatePrice(item.pr_rmb_sale, 1,1) ]} {[ suihuo_tips(item.pr_am, item.pr_size) ]}

{[ getRatePrice(item.pr_rmb, 1,1) ]}

{[ getRatePrice(item.pr_rmb,item.pr_rate,1) ]} {[ suihuo_tips(item.pr_am, item.pr_size) ]} 		{[ getRatePrice(item.pr_rmb, 1,1) ]}{[ suihuo_tips(item.pr_am, item.pr_size) ]} {[ getRatePrice(item.pr_rmb_sale, 1,1) ]} {[ getRatePrice(item.pr_rmb,item.pr_rate,item.mem_rate) ]} {[ getRatePrice(item.pr_rmb,1,item.mem_rate) ]} 现货 咨询 - +
购物车0 收藏 询单

Vitamin B12 纯度/质量文件 产品仅供科研

货号：A884890 标准纯度： {[allProObj[0].p_purity_real_show]}
批次查询： 批次纯度:

全球学术期刊中引用的产品

• Cell Host Microbe, 2024. Ambeed. [ A163338 ]
• Cancer Res., 2024. Ambeed. [ A295334 ]
• J. Pharm. Investig., 2024. Ambeed. [ A221527 , A691302 , A272538 , A187261 ]
• J. Fungi, 2024, 10(11): 751. Ambeed. [ A796919 ]
• JBC, 2024, 107935. Ambeed. [ A194396 ]
更多 >

Vitamin B12 生物活性

描述 Vitamin B12 is a water soluble vitamin with a key role in the normal functioning of the brain and nervous system, and for the formation of blood. Vitamin B12 is a complex organometallic cofactor associated with three subfamilies of enzymes: the adenosylcobalamin-dependent isomerases, the methylcobalamin-dependent methyltransferases, and the dehalogenases[3]. Light excitation energy can promote covalent linkage of B12 to transcription factors with this linkage, affecting gene expression[4]. Vitamin B12 is synthesized in some bacteria but not in animals and plants. Intestinal absorption and subsequent plasma transport of vitamin B12 are mediated by specific vitamin B12-binding proteins and their receptors in mammals. Vitamin B12 taken up by the cells is enzymatically converted to coenzyme forms of vitamin B12, methyl- and adenosyl-vitamin B12, which function as coenzymes of methionine synthase (EC 2.1.13), involved in methionine biosynthesis, and methylmalonyl-CoA mutase (EC 5.4.99.2), involved in oxidation of odd-numbered fatty acids and amino acids (valine, isoleucine, and threonine), respectively[5].

Vitamin B12 参考文献

[1]Moore SJ, Lawrence AD, et al. Elucidation of the anaerobic pathway for the corrin component of cobalamin (vitamin B12). Proc Natl Acad Sci U S A. 2013 Sep 10;110(37):14906-11.

[2]Banerjee R, Ragsdale SW. The many faces of vitamin B12: catalysis by cobalamin-dependent enzymes. Annu Rev Biochem. 2003;72:209-47.

[3]Banerjee R, Ragsdale SW. The many faces of vitamin B12: catalysis by cobalamin-dependent enzymes. Annu Rev Biochem. 2003;72:209-247

[4]Cheng Z, Yamamoto H, Bauer CE. Cobalamin's (Vitamin B12) Surprising Function as a Photoreceptor. Trends Biochem Sci. 2016;41(8):647-650

[5]Watanabe F, Nakano Y. Nihon Rinsho. 1999;57(10):2205-2210

Vitamin B12 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

0.74mL

0.15mL

0.07mL

3.69mL

0.74mL

0.37mL

7.38mL

1.48mL

0.74mL

Vitamin B12 技术信息

CAS号68-19-9
分子式C63H88CoN14O14P
分子量 1355.365
别名 Cyanocobalamin;Cobalamin;NSC 80365;Docigram
运输蓝冰
存储条件

液体 -20°C:3-6个月-80°C:12个月

粉末 Inert atmosphere,2-8°C
溶解度

DMSO: 20 mg/mL(14.76 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

H2O: 6 mg/mL(4.43 mM)，配合低频超声，并水浴加热至45℃助溶
动物实验配方

Tags: Vitamin B12 | Cyanocobalamin;Cobalamin;NSC 80365;Docigram | Additive and Auxiliary Reagent | Vitamin | AmBeed-信号通路专用抑制剂 | Vitamin B12 纯度/质量文件 | Vitamin B12 生物活性 | Vitamin B12 参考文献 | Vitamin B12 实验方案 | Vitamin B12 技术信息

Ambeed 相关网站 Ambeed.cn Ambeed.com
Ambeed
关于我们
联系我们
资讯中心
网站地图
产品手册
  • 批次文件查询
    • 客户支持
    技术支持
    专业术语
    缩略词释义
    质量手册
    产品咨询
    计算器
    活动政策
    订购方法
    积分商城
    活动声明
    联系我们
    400-920-2911 sales@ambeed.cn tech@ambeed.cn
    Ambeed 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质用途提供服务。

    尊敬的 Ambeed 客户您好，
    请您选择所在区域，我们将转接对应客服为您服务！

    热门区域

    A

    B

    C

    F

    G

    H

    J

    L

    N

    Q

    S

    T

    X

    Y

    Z

    热 A B C F G H J L N Q S T X Y Z