曲克芦丁 /Troxerutin
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货号：A105819
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维脑路通
/ Trihydroxyethylrutin;Vitamin P4
Troxerutin, also known as vitamin P4, can inhibit platelet aggregation and the production of ROS. It is a flavonol isolated from Sophora japonica and used as a vasoprotective.
Troxerutin 化学结构
Troxerutin 3D分子结构
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Troxerutin 纯度/质量文件 产品仅供科研
货号：A105819
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Troxerutin 质控信息
Troxerutin 生物活性
描述
Troxerutin, is natural flavonoid rutin present in tea, coffee, cereal grains and a variety of fruits and vegetables. It can improve capillary function, reduce capillary fragility and abnormal leakage. Toxerutin preconditioning significantly reduced myocardial infarct size, improved cardiac function[3] [4] [5]
Troxerutin 参考文献
[1] Boisseau MR, Taccoen A, et al. Fibrinolysis and hemorheology in chronic venous insufficiency: a double blind study of troxerutin efficiency. J Cardiovasc Surg (Torino). 1995 Aug;36(4):369-74.
[2] Olszewski AJ, Szostak WB, et al. Reduction of plasma lipid and homocysteine levels by pyridoxine, folate, cobalamin, choline, riboflavin, and troxerutin in atherosclerosis. Atherosclerosis. 1989 Jan;75(1):1-6. Erratum in: Atherosclerosis 1991 May;88(1):978.
[3] Shu L, Zhang W, Huang C, Huang G, Su G. Troxerutin Protects Against Myocardial Ischemia/Reperfusion Injury Via Pi3k/Akt Pathway in Rats. Cell Physiol Biochem. 2017;44(5):1939-1948. doi: 10.1159/000485884. Epub 2017 Dec 8. PMID: 29241161.
[4] Yu Y, Zheng G. Troxerutin protects against diabetic cardiomyopathy through NF‑κB/AKT/IRS1 in a rat model of type 2 diabetes. Mol Med Rep. 2017 Jun;15(6):3473-3478. doi: 10.3892/mmr.2017.6456. Epub 2017 Apr 11. PMID: 28440404; PMCID: PMC5436284.
[5] Shan Q, Zheng GH, Han XR, Wen X, Wang S, Li MQ, Zhuang J, Zhang ZF, Hu B, Zhang Y, Zheng YL. Troxerutin Protects Kidney Tissue against BDE-47-Induced Inflammatory Damage through CXCR4-TXNIP/NLRP3 Signaling. Oxid Med Cell Longev. 2018 Apr 19;2018:9865495. doi: 10.1155/2018/9865495. PMID: 29849929; PMCID: PMC5932985.
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Troxerutin 实验方案
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1mg
5mg
10mg
1 mM
5 mM
10 mM
1.35mL
0.27mL
0.13mL
6.73mL
1.35mL
0.67mL
13.46mL
2.69mL
1.35mL
Troxerutin 技术信息
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