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/ Temoporfin

替莫泊芬 /Temoporfin {[allProObj[0].p_purity_real_show]}

货号：A437476 同义名： 替莫卟吩 / m-THPC;KW2345

Temoporfin is used in photodynamic therapy for the treatment of squamous cell carcinoma of the head and neck.

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There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Temoporfin 化学结构 CAS号：122341-38-2
Temoporfin 化学结构
CAS号：122341-38-2
Temoporfin 3D分子结构
CAS号：122341-38-2
Temoporfin 化学结构 CAS号：122341-38-2
Temoporfin 3D分子结构 CAS号：122341-38-2
规格 价格 会员价 库存 数量
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Temoporfin 纯度/质量文件 产品仅供科研

货号：A437476 标准纯度： {[allProObj[0].p_purity_real_show]}
批次查询： 批次纯度:

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Temoporfin 生物活性

描述 Temoporfin is used in photodynamic therapy for the treatment of squamous cell carcinoma of the head and neck.

Temoporfin 临床研究

NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT00003856 Head and Neck Cancer Phase 2 Unknown - United States, Arkansas ... 展开 >> University of Arkansas for Medical Sciences Little Rock, Arkansas, United States, 72205 United States, Florida H. Lee Moffitt Cancer Center and Research Institute Tampa, Florida, United States, 33612 United States, Illinois Division of Head and Neck Surgery Evanston, Illinois, United States, 60201 United States, Kentucky Norton Healthcare Pavilion Louisville, Kentucky, United States, 40202 United States, Minnesota Ear, Nose, and Throat Specialty Care of Minnesota, P.A. Minneapolis, Minnesota, United States, 55404 United States, New York School of Dental Medicine Buffalo, New York, United States, 14214-3008 St. Luke's-Roosevelt Hospital New York, New York, United States, 10019 收起 <<
NCT01086488 Nasopharyngeal Carcinoma Phase 2 Unknown October 2011 Malaysia ... 展开 >> Hospital Universiti Sains Malaysia Not yet recruiting Kubang Kerian, Kelantan, Malaysia, 16150 Contact: Baharudin Abdullah, MD    0139825050    baharudin@kb.usm.my    Contact: Biswal Mohan, MD    +6097653370       Queen Elizabeth Hospital Not yet recruiting Kota Kinabalu, Sabah, Malaysia Contact: Chee Lun Lum, MD    +6088318605       Contact: Jayendran Dharmaratnam, MD    +6088438512    navinsurfer@hotmail.com    Universiti Malaysia Sarawak Not yet recruiting Kuching, Sarawak, Malaysia, 93150 Contact: Thung Sing Tiong, MD    +6082422564       Contact: Vignes Tharumalingam, MD    01620900002       Kuala Lumpur Hospital Recruiting Kuala Lumpur, Malaysia, 53000 Contact: Yoke Yeow Yap, MD    +60320501001    yokeyeow@yahoo.com    Contact: Azura Deniel, MD    +60326925713    azurahkl@yahoo.com    Hospital Pulau Pinang Not yet recruiting Penang, Malaysia Contact: Kin Choo Pua, MD    +6044105463    puakinchoo@pph.moh.gov.my 收起 <<
NCT01718223 Recurrent Squamous Cell Carcin... 展开 >>oma of the Lip and Oral Cavity Recurrent Squamous Cell Carcinoma of the Oropharynx Recurrent Verrucous Carcinoma of the Oral Cavity Stage I Squamous Cell Carcinoma of the Lip and Oral Cavity Stage I Squamous Cell Carcinoma of the Oropharynx Stage I Verrucous Carcinoma of the Oral Cavity Stage II Squamous Cell Carcinoma of the Lip and Oral Cavity Stage II Squamous Cell Carcinoma of the Oropharynx Stage II Verrucous Carcinoma of the Oral Cavity Tongue Cancer 收起 << Not Applicable Withdrawn(implementation issue... 展开 >>s) 收起 << - -

Temoporfin 参考文献

[1]Kralova J, Kolar M, et al. Glycol porphyrin derivatives and temoporfin elicit resistance to photodynamic therapy by different mechanisms. Sci Rep. 2017 Mar 15;7:44497.

[2]Wagner A, Denzer UW, et al. Temoporfin improves efficacy of photodynamic therapy in advanced biliary tract carcinoma: A multicenter prospective phase II study. Hepatology. 2015 Nov;62(5):1456-65.

Temoporfin 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.47mL

0.29mL

0.15mL

7.34mL

1.47mL

0.73mL

14.69mL

2.94mL

1.47mL

Temoporfin 技术信息

CAS号122341-38-2
分子式C44H32N4O4
分子量 680.749
别名 替莫卟吩 ;m-THPC;KW2345;Fospeg.;Foslipos;Foslip;Fosgel;Generic name: temoporfin. Brand name: Foscan;8-​Dihydroporphyrin-​5;5,​10,​15,​20-​Tetrakis(m-​hydroxyphenyl)​chlorin;5,​10,​15,​20-​Tetra(m-​hydroxyphenyl)​chlorin;3,​3',​3'',​3'''-​(7,​8-​Dihydroporphyrin-​5,​10,​15,​20-​tetrayl)​tetraphenol;EF 9;Foscan
运输蓝冰
存储条件

液体 -20°C:3-6个月-80°C:12个月

粉末 Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
溶解度

DMSO: 20 mg/mL(29.38 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方

Tags: Temoporfin | 122341-38-2 | m-THPC | KW2345 | KW2345 | KW 2345 | KW-2345 | Immunology/Inflammation | NF-κB | Metabolic Enzyme/Protease | Reactive Oxygen Species | 仅供科研使用 | AmBeed-信号通路专用抑制剂 | Temoporfin 纯度/质量文件 | Temoporfin 生物活性 | Temoporfin 临床数据 | Temoporfin 参考文献 | Temoporfin 实验方案 | Temoporfin 技术信息

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