产品说明书
Temoporfin
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同义名 : | 替莫卟吩 ;m-THPC;KW2345;Fospeg.;Foslipos;Foslip;Fosgel;Generic name: temoporfin. Brand name: Foscan;8-Dihydroporphyrin-5;5,10,15,20-Tetrakis(m-hydroxyphenyl)chlorin;5,10,15,20-Tetra(m-hydroxyphenyl)chlorin;3,3',3'',3'''-(7,8-Dihydroporphyrin-5,10,15,20-tetrayl)tetraphenol;EF 9;Foscan |
| CAS号 : | 122341-38-2 | |
| 货号 : | A437476 | |
| 分子式 : | C44H32N4O4 | |
| 纯度 : | 98% | |
| 分子量 : | 680.749 | |
| MDL号 : | MFCD00867835 | |
| 存储条件： |
粉末 Keep in dark place,Inert atmosphere,Store in freezer, under -20°C 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 20 mg/mL(29.38 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Temoporfin is used in photodynamic therapy for the treatment of squamous cell carcinoma of the head and neck. | ||
| 临床研究 | |||||
|---|---|---|---|---|---|
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
| NCT00003856 | Head and Neck Cancer | Phase 2 | Unknown | - | United States, Arkansas ... 展开 >> University of Arkansas for Medical Sciences Little Rock, Arkansas, United States, 72205 United States, Florida H. Lee Moffitt Cancer Center and Research Institute Tampa, Florida, United States, 33612 United States, Illinois Division of Head and Neck Surgery Evanston, Illinois, United States, 60201 United States, Kentucky Norton Healthcare Pavilion Louisville, Kentucky, United States, 40202 United States, Minnesota Ear, Nose, and Throat Specialty Care of Minnesota, P.A. Minneapolis, Minnesota, United States, 55404 United States, New York School of Dental Medicine Buffalo, New York, United States, 14214-3008 St. Luke's-Roosevelt Hospital New York, New York, United States, 10019 收起 << |
| NCT01086488 | Nasopharyngeal Carcinoma | Phase 2 | Unknown | October 2011 | Malaysia ... 展开 >> Hospital Universiti Sains Malaysia Not yet recruiting Kubang Kerian, Kelantan, Malaysia, 16150 Contact: Baharudin Abdullah, MD 0139825050 baharudin@kb.usm.my Contact: Biswal Mohan, MD +6097653370 Queen Elizabeth Hospital Not yet recruiting Kota Kinabalu, Sabah, Malaysia Contact: Chee Lun Lum, MD +6088318605 Contact: Jayendran Dharmaratnam, MD +6088438512 navinsurfer@hotmail.com Universiti Malaysia Sarawak Not yet recruiting Kuching, Sarawak, Malaysia, 93150 Contact: Thung Sing Tiong, MD +6082422564 Contact: Vignes Tharumalingam, MD 01620900002 Kuala Lumpur Hospital Recruiting Kuala Lumpur, Malaysia, 53000 Contact: Yoke Yeow Yap, MD +60320501001 yokeyeow@yahoo.com Contact: Azura Deniel, MD +60326925713 azurahkl@yahoo.com Hospital Pulau Pinang Not yet recruiting Penang, Malaysia Contact: Kin Choo Pua, MD +6044105463 puakinchoo@pph.moh.gov.my 收起 << |
| NCT01718223 | Recurrent Squamous Cell Carcin... 展开 >>oma of the Lip and Oral Cavity Recurrent Squamous Cell Carcinoma of the Oropharynx Recurrent Verrucous Carcinoma of the Oral Cavity Stage I Squamous Cell Carcinoma of the Lip and Oral Cavity Stage I Squamous Cell Carcinoma of the Oropharynx Stage I Verrucous Carcinoma of the Oral Cavity Stage II Squamous Cell Carcinoma of the Lip and Oral Cavity Stage II Squamous Cell Carcinoma of the Oropharynx Stage II Verrucous Carcinoma of the Oral Cavity Tongue Cancer 收起 << | Not Applicable | Withdrawn(implementation issue... 展开 >>s) 收起 << | - | - |
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
1.47mL 0.29mL 0.15mL |
7.34mL 1.47mL 0.73mL |
14.69mL 2.94mL 1.47mL |
| 参考文献 |
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