Sulconazole nitrate is an imidazole derivative with broad-spectrum antifungal activity.
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Sulconazole mononitrate ((±)-Sulconazole mononitrate), an imidazole derivative, serves as a broad-spectrum antifungal agent. It is utilized in the study of various fungal skin infections including dermatomycoses, pityriasis versicolor, and cutaneous candidiasis[1].[2].
体外研究
Sulconazole mononitrate exhibits a broad spectrum of antifungal activity, effectively inhibiting the growth of dermatophytes, yeasts, and various filamentous and dimorphic fungi at concentrations below 5 mg/L in vitro[1].
Sulconazole mononitrate also shows antibacterial activity, with minimum inhibitory concentrations (MIC) below 12.5 mg/L against several Staphylococcus species, Streptococcus faecalis, and certain gram-positive anaerobes[1].
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