Punicalagin, a natural product isolated and purified from the peel of Punica granatum L., is a potential alternative or supplemental agent for prevention of Salmonella infection, has a greater antifungal activity against T.
Punicalagin, a natural product isolated and purified from the peel of Punica granatum L., is a potential alternative or supplemental agent for prevention of Salmonella infection, has a greater antifungal activity against T[3]. Punicalagin (100 mg/ml) induces apoptosis in HT-29, HCT116 colon cells[4]. Punicalagin significantly attenuated, in a concentration-dependent manner, LPS-induced release of NO and decreased pro-inflammatory cytokines TNF-α and IL-6 release at the highest concentration[5]. Punicalagin slightly inhibits the PLpro activity with an IC50 of over 50 μM. Punicalagin inhibits the plaque formation of SARS-CoV-2 in a dose-dependent manner, with EC50 values of 7.20 μM[6]. Punicalagin (10 mg/kg) inhibits the edema rate of 58.15% in rats[7].
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