There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.
Type
HazMat fee for 500 gram (Estimated)
Excepted Quantity
USD 0.00
Limited Quantity
USD 15-60
Inaccessible (Haz class 6.1), Domestic
USD 80+
Inaccessible (Haz class 6.1), International
USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic
USD 100+
Accessible (Haz class 3, 4, 5 or 8), International
Pipemidic acid, a derivative of piromidic acid, is an antibacterial agent that targets DNA gyrase. It is effective against gram-negative bacteria, including Pseudomonas aeruginosa, and some gram-positive bacteria, making it applicable in researching intestinal, urinary, and biliary tract infections[1].[2].
体内研究
When administered orally, pipemidic acid (50 mg/kg) is well absorbed, with peak plasma levels ranging from 4 to 12 μg/mL observed in mice, rats, dogs, and monkeys[3].
The mean lethal dose (LD50) of pipemidic acid, following a single oral dose, was found to exceed 16000 mg/kg in mice, indicating a high safety margin[3].
体外研究
Pipemidic acid acts by inhibiting DNA gyrase, a bacterial enzyme responsible for the ATP-dependent negative supercoiling of DNA[2].
搜索
HazMat Fee +
