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球松素 /Pinostrobin {[allProObj[0].p_purity_real_show]}

货号:A305777

Pinostrobin, a natural product isolated and purified from the herbs of Cajanus cajan with anti-inflammatory, cytotoxic, anti-hemorrhagic and analgesic activities, exerts a neuroprotective effect against Aβ(25-35)-induced neurotoxicity in PC12 cells, at least in part, via inhibiting oxidative damage and calcium overload, as well as suppressing the mitochondrial pathway of cellular apoptosis, and can inhibit HSV-1 replication with 50% effective concentration (EC(50)) of 22.71 ± 1.72 ug/mL.

Pinostrobin 化学结构 CAS号:480-37-5
Pinostrobin 化学结构
CAS号:480-37-5
Pinostrobin 3D分子结构
CAS号:480-37-5
Pinostrobin 化学结构 CAS号:480-37-5
Pinostrobin 3D分子结构 CAS号:480-37-5
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Pinostrobin 纯度/质量文件 产品仅供科研

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Pinostrobin 生物活性

描述 Pinostrobin, a natural product isolated and purified from the herbs of Cajanus cajan with anti-inflammatory, cytotoxic, anti-hemorrhagic and analgesic activities, exerts a neuroprotective effect against Aβ(25-35)-induced neurotoxicity in PC12 cells, at least in part, via inhibiting oxidative damage and calcium overload, as well as suppressing the mitochondrial pathway of cellular apoptosis, and can inhibit HSV-1 replication with 50% effective concentration (EC(50)) of 22.71 ± 1.72 ug/mL.

Pinostrobin 参考文献

[1]Gomez-Betancur I, Benjumea D, et al. Inhibition of the toxic effects of Bothrops asper venom by pinostrobin, a flavanone isolated from Renealmia alpinia (Rottb.) MAAS. J Ethnopharmacol. 2014 Sep 29;155(3):1609-15.

[2]Patel NK, Bhutani KK. Pinostrobin and Cajanus lactone isolated from Cajanus cajan (L.) leaves inhibits TNF-α and IL-1β production: in vitro and in vivo experimentation. Phytomedicine. 2014 Jun 15;21(7):946-53.

Pinostrobin 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.70mL

0.74mL

0.37mL

18.50mL

3.70mL

1.85mL

37.00mL

7.40mL

3.70mL

Pinostrobin 技术信息

CAS号480-37-5
分子式C16H14O4
分子量 270.28
别名
运输蓝冰
存储条件

液体 -20°C:3-6个月-80°C:12个月

粉末 Sealed in dry,2-8°C

溶解度

DMSO: 105 mg/mL(388.49 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方
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