PKSI-527是一种新型、高选择性的血浆激肽释放酶抑制剂，通过调节激肽系统，能够有效抑制胶原诱导的关节炎 (CIA)，适用于关节炎及相关炎症疾病的研究。

PCSK9-IN-13 是一种有效的 PCSK9 抑制剂，通过与 PCSK9 结合来拮抗低密度脂蛋白 (LDL) 受体的结合，其 IC50 为 537 nM。

NSC95682 is a derivative of bromobenzaldehyde which can inhibit inositol-requiring enzyme 1 α (IRE-1α) with IC50 of 0.08 μM.

1-Methylguanidine hydrochloride是一种内源性代谢产物。

Hepln-13 is a potent and orally active Hepsin inhibitor with an IC50 of 0.33 µM.

TAO Kinase inhibitor 2是一种 TAO 激酶抑制剂，IC₅₀ 值为 50-500 nM，并能抑制其他激酶如 KIAA1361 和 JIK，广泛用于细胞信号传导通路的研究。

SBC-115337是一种有效的 PCSK9 抑制剂，IC₅₀ 值为 0.5 μM。该化合物通过抑制 PCSK9 与 LDL 受体的相互作用，减少 LDL-C 水平，具有控制血脂异常和心血管疾病的潜力。

PCSK9-IN-10是一种有效的口服 PCSK9 抑制剂，IC50 值为 6.4 μM，可增加 LDLR 蛋白表达并降低 PCSK9 表达，减缓动脉粥样硬化进展，可用于高脂血症研究。

SBC-115076 is an anti-proprotein convertase subtilisin kexin type 9 (anti-PCSK9) compounds, for the treatment and/or prevention of cardiovascular diseases.

WNK1-IN-1是一种选择性WNK1激酶抑制剂，通过调节离子通道和细胞体液平衡，具有用于治疗高血压和心血管疾病的潜力。

PCSK9-IN-12是一种杂环化合物，对PCSK9具有Kd值<200 nM的结合亲和力。可用于胆固醇代谢研究。

Sebetralstat是一种血浆激肽酶(Plasma kallikrein)抑制剂，用于治疗遗传性血管性水肿等代谢疾病的研究。

GSK'872 is an inhibitor of RIPK3 with IC50 of 1.8 nM and kinase activity (IC50 = 1.3 nM). It also exhibits supression of necrosis induced by toll-like receptor 3.

FOY-251 is a metabolite of Camostat that acts as a pollen protease inhibitor for prevention and control of allergies.

Fulacimstat 是一种口服可利用的胰凝乳蛋白酶抑制剂，对人和仓鼠胰凝乳蛋白酶的 IC50 值分别为 4 nM 和 3 nM。

3,4 Dichloroisocoumarin is a potent, irreversible inhibitor of serine proteases. It reacts with serine proteases to release an acylchloride moiety that can acylate another active site residue. 3,4 Dichloroisocoumarin also inhibits granzymes A, B, and H, cathepsin G, neutrophil elastase, proteinase and blocks apoptotic internucleosomal DNA cleavage in thymocytes without the involvement of endonucleases. 3,4 Dichloroisocoumarin inhibits activation of neutral sphingomyelinase and daunorubicin-triggered apoptosis as well as apoptosis induced by camptothecin in HL-60 cells. 3,4 Dichloroisocoumarin inhibits migration of eosinophils through basement membrane components in vitro. 3,4 Dichloroisocoumarin does not affect thiol proteases and metalloproteases. 3,4 Dichloroisocoumarin does not exhibit any activity towards β-lactamases. 3,4 Dichloroisocoumarin is an inhibitor of Chymotrypsin and Trypsin.

Bradykinin is a pro-inflammatory polypeptide. It is an important mediator of hyperalgesia, inflammatory diseases, asthma and cancer with anti-cancer activities. Targeting the bradykinin system by either blocking the bradykinin production may open a new potential therapeutic window for the treatment of COVID-19 induced acute respiratory distress syndrome (ARDS) particularly before patients enter the irreversible stages.

SBC-110736 is an inhibitor of proprotein convertase subtilisin kexin type 9 (PCSK9), lowering cholesterol levels in mice.

Avoralstat（BCX4161）是一种有效的口服活性血浆激肽酶抑制剂，用于研究遗传性血管性水肿。 Polygalaxanthone III抑制CYP450酶，并通过其IC50为50.56μM的CYP2E1催化的氯索磺酮6-羟基化来抑制。

7H-Purin-2-amine, isomer of adenine, is an inhibitor of protein kinase R (PKR) with antimetabolite effect.