There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.
Type
HazMat fee for 500 gram (Estimated)
Excepted Quantity
USD 0.00
Limited Quantity
USD 15-60
Inaccessible (Haz class 6.1), Domestic
USD 80+
Inaccessible (Haz class 6.1), International
USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic
USD 100+
Accessible (Haz class 3, 4, 5 or 8), International
Horseradish peroxidase (HRP) actively participates in the oxidation of reactive oxygen species, innate immunity, hormone biosynthesis, and the pathogenesis of several diseases[1]. Myeloperoxidase (MPO), found in human white blood cells, is a peroxidase enzyme. It plays a role in mediating oxidative stress by facilitating the generation of reactive oxygen species (ROS) and active nitrogen (RNS), while also modulating the polarization and inflammation-related signaling pathways in microglia and neutrophils. Additionally, MPO exhibits antibacterial activity[1][2].
Lactoperoxidase (LPO) from bovine milk is an antimicrobial protein classified within the mammalian heme peroxidase family. Lactoperoxidase utilizes H2O2 to catalyze the oxidation of its preferred halide substrates, which include I−, Br−, F−, or the pseudohalide SCN−[1].
体外研究
Peroxidases constitute a diverse family of isoenzymes found across nearly all living organisms. Typically heme-containing enzymes, they exhibit molecular weights ranging from 35-100 kDa. Mammalian peroxidases are notably larger proteins (576-738 amino acids) compared to their plant counterparts. These enzymes may exist as monomers, dimers, or tetramers, with their gene loci dispersed across various chromosomes. Additionally, peroxidases exhibit distinct distribution patterns at the organ, tissue, cellular, and subcellular levels, each performing specialized functions[1].
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