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Peroxidase, Horseradish

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Chemical Structure| 9003-99-0 同义名 : -
CAS号 : 9003-99-0
货号 : A287335
分子式 : N/A
纯度 : ≥150u/mg
分子量 : 0
MDL号 : MFCD00071339
存储条件:

粉末 Inert atmosphere,2-8°C

液体 -20°C:3-6个月-80°C:12个月

溶解度 :

H2O: 30 mg/mL,配合低频超声,并水浴加热至45℃助溶

动物实验配方:
生物活性
描述 Horseradish peroxidase (HRP) actively participates in the oxidation of reactive oxygen species, innate immunity, hormone biosynthesis, and the pathogenesis of several diseases[1]. Myeloperoxidase (MPO), found in human white blood cells, is a peroxidase enzyme. It plays a role in mediating oxidative stress by facilitating the generation of reactive oxygen species (ROS) and active nitrogen (RNS), while also modulating the polarization and inflammation-related signaling pathways in microglia and neutrophils. Additionally, MPO exhibits antibacterial activity[1][2]. Lactoperoxidase (LPO) from bovine milk is an antimicrobial protein classified within the mammalian heme peroxidase family. Lactoperoxidase utilizes H2O2 to catalyze the oxidation of its preferred halide substrates, which include I, Br, F, or the pseudohalide SCN[1].
参考文献

[1]Khan AA, et al. Biochemical and pathological studies on peroxidases -an updated review. Glob J Health Sci. 2014 May 13;6(5):87-98.

[2]Parker H, et al. Myeloperoxidase associated with neutrophil extracellular traps is active and mediates bacterial killing in the presence of hydrogen peroxide. J Leukoc Biol. 2012 Mar;91(3):369-76.