Penicillin G sodium is a typical β-lactam antibiotic. Intravenous administration of a total dose of more than 200 million IU of penicillin-G led to sensitisation of lymphocytes and formation of specific anti-penicilloyl antibodies of the IgG class[2]. Intrapartum penicillin G prophylaxis aims to prevent early-onset group B streptococci (GBS) sepsis by interrupting vertical transmission[3]. High-dose intravenous therapy with penicillin-G always results in both sensitised lymphocytes and rise of anti-penicilloyl IgG antibodies. Strict application of freshly prepared single doses prevents the majority of adverse reactions following highdose intravenous penicillin-G therapy[4]. The addition of citrate buffer to a penicillin G preparation for injection was in a preliminary study found to improve the local tolerance in rabbits. The local tolerance may influence the serum levels in a way that may influence the penetration of penicillin[5]. Most Gram-negative urinary pathogens are sensitive to 5-50 mug of penicillin G per ml. There is a rational basis for the use of oral penicillin G to treat urinary infection due to Gram-negative bacilli[6].
Tags:
Penicillin G sodium salt
|青霉素G钠盐
| 青霉素钠
| Benzylpenicillin sodium salt
| Benzylpenicillin Sodium
| Penicillin G Sodium
| 69-57-8
| 青霉素类
| 抗真菌抗生素
| 药物标准品
| 类器官培养添加剂
| Antibacterial
| Penicillin G sodium salt 纯度/质量文件
| Penicillin G sodium salt 生物活性
| Penicillin G sodium salt 参考文献
| Penicillin G sodium salt 实验方案
| Penicillin G sodium salt 技术信息
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