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南昌霉素 /Nanchangmycin {[allProObj[0].p_purity_real_show]}

货号:A581200 同义名: Nanchangmycin A

Nanchangmycin is a polyether antibiotic with similar structure to dianemycin and is very active against a broad spectrum of harmful nematodes and insects but not for mammals and plants.

HazMat Fee +

There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Nanchangmycin 化学结构 CAS号:65101-87-3
Nanchangmycin 化学结构
CAS号:65101-87-3
Nanchangmycin 3D分子结构
CAS号:65101-87-3
Nanchangmycin 化学结构 CAS号:65101-87-3
Nanchangmycin 3D分子结构 CAS号:65101-87-3
规格 价格 会员价 库存 数量
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Nanchangmycin 纯度/质量文件 产品仅供科研

货号:A581200 标准纯度: {[allProObj[0].p_purity_real_show]}
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Nanchangmycin 生物活性

描述 Nanchangmycin is a polyether antibiotic derived from Streptomyces nanchangensis NS3226, known for its inhibitory action against gram-positive bacteria[1]. Nanchangmycin, recognized as a broad-spectrum antiviral, is effective against the Zika virus. Nanchangmycin is a strong inhibitor of Zika virus (ZIKV) entry in all tested cell types, including primary cells that are physiologically significant. It effectively reduces infections by all three ZIKV strains in these cell types, with IC50 values ranging from 0.1 to 0.4 μM, and exhibits low toxicity within these concentrations. Additionally, Nanchangmycin also inhibits the Dengue virus (DENV) across various cell types[2].

Nanchangmycin 参考文献

[1]Liu T et al. Mechanism of thioesterase-catalyzed chain release in the biosynthesis of the polyether antibiotic nanchangmycin. Chem Biol. 2008 May;15(5):449-58.

[2]Rausch K, et al. Screening Bioactives Reveals Nanchangmycin as a Broad Spectrum Antiviral Active against Zika Virus. Cell Rep. 2017 Jan 17;18(3):804-815.

Nanchangmycin 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.12mL

0.22mL

0.11mL

5.62mL

1.12mL

0.56mL

11.25mL

2.25mL

1.12mL

Nanchangmycin 技术信息

CAS号65101-87-3
分子式C47H77NaO14
分子量 889.096
别名 Nanchangmycin A
运输蓝冰
存储条件

液体 -20°C:3-6个月-80°C:12个月

粉末 Keep in dark place,Inert atmosphere,2-8°C

溶解度

DMSO: 105 mg/mL(118.1 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方
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