There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.
Type
HazMat fee for 500 gram (Estimated)
Excepted Quantity
USD 0.00
Limited Quantity
USD 15-60
Inaccessible (Haz class 6.1), Domestic
USD 80+
Inaccessible (Haz class 6.1), International
USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic
USD 100+
Accessible (Haz class 3, 4, 5 or 8), International
NSC232003 is a uracil derivative that can be used as a versatile lead compound for the development of UHRF1 inhibitors that can be used to analyse DNA methylation genetically.NSC232003 can be used as a potent DNA methylation inhibitor. NSC232003 was predicted to partially deprotonate the more acidic imide nitrogen on the pyrimidine ring at pH 7.6. After incubating U251 glioma cells with NSC232003 for 4 h, the interaction of DNMT1/UHRF1 was significantly attenuated, with 50% inhibition of the interaction at 15 μM, and DNMT1/UHRF1 induced global DNA cytosine deprotonation, as determined by ELISA [1].
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