Kazinol U, a natural product isolated and purified from the barks of Broussonetia papyrifera, may have therapeutic value in delaying pancreatic β-cell destruction in type 1 diabetes by blocking theNF-κB pathway in pancreatic β-cells reduces cell damage.
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产品名称 | AMPK ↓ ↑ | 其他靶点 | 纯度 | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
WZ4003 |
++++
NUAK2, IC50: 100 nM NUAK1, IC50: 20 nM | 98+% | |||||||||||||||||
Dorsomorphin |
++
AMPK, Ki: 109 nM | 99% | |||||||||||||||||
HTH-01-015 |
+++
NUAK1 , IC50: 100 nM | 99%+ | |||||||||||||||||
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。 |
描述 | Kazinol U, a natural product isolated and purified from the barks of Broussonetia papyrifera, may have therapeutic value in delaying pancreatic β-cell destruction in type 1 diabetes by blocking the NF-κB pathway in pancreatic β-cells reduces cell damage. |
计算器 | ||||
存储液制备 | ![]() | 1mg | 5mg | 10mg |
1 mM 5 mM 10 mM | 3.06mL 0.61mL 0.31mL | 15.32mL 3.06mL 1.53mL | 30.64mL 6.13mL 3.06mL |
CAS号 | 1238116-48-7 |
分子式 | C20H22O4 |
分子量 | 326.386 |
别名 | |
运输 | 蓝冰 |
存储条件 | In solvent -20°C:3-6个月-80°C:12个月 Pure form |
溶解方案 | |
动物实验配方 |