Isoconazole nitrate | Isoconazole (nitrate) | Bacterial Inhibitor

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硝酸异康唑 /Isoconazole nitrate {[allProObj[0].p_purity_real_show]}

货号：A113906 同义名： Isoconazole (nitrate);R 15454

Isoconazole Nitrate is a broad-spectrum antimicrobial agent with a highly effective antimycotic and gram-positive antibacterial activity and is effective in the treatment of dermatomycoses.

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Isoconazole nitrate 化学结构
CAS号：24168-96-5

Isoconazole nitrate 3D分子结构
CAS号：24168-96-5

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Isoconazole nitrate 纯度/质量文件产品仅供科研

货号：A113906 标准纯度： {[allProObj[0].p_purity_real_show]} 产品说明书

批次查询：批次纯度: COA SDS NMR HPLC CNMR LC-MS

全球学术期刊中引用的产品: • JACS Au, 2024. Ambeed. [ A148168 ]; • JMC, 2024. Ambeed. [ A187643 ]; • JMC, 2024. Ambeed. [ A341145 , A633512 , A607865 , A167774 ]; • Biomacromolecules, 2024. Ambeed. [ A110759 ]; • Biomacromolecules, 2024. Ambeed. [ A203543 ]; 更多 >

Isoconazole nitrate 生物活性

描述

Isoconazole nitrate (ISN) is a broad-spectrum antimicrobial agent with a highly effective antimycotic and gram-positive antibacterial activity, a rapid rate of absorption and low systemic exposure potential. ISN is effective against pathogens involved in dermatomycoses, with minimum inhibitory concentrations well below the concentration of ISN in skin and hair follicles^[3]. Treatment results with the combination of isoconazole nitrate and diflucortolone valerate were superior regarding erythema and pruritus^[4]. 1% isoconazole nitrat is more effective than a commercial cream containing 1% clotrimazole^[5].

Isoconazole nitrate 临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
NCT00722189	-		Completed	-	Russian Federation ... 展开 >> Kashkin Clinical Research Mycological Institute St Petersburg, Russian Federation 收起 <<

Isoconazole nitrate 参考文献

[1]Bianchi L, Hansel K, et al. Contact allergy to isoconazole nitrate with unusual spreading over extensive regions. Contact Dermatitis. 2017 Apr;76(4):243-245.

[2]Czaika VA, Siebenbrock J, et al. Reactive oxygen species and the bacteriostatic and bactericidal effects of isoconazole nitrate. Mycoses. 2013 May;56 Suppl 1:16-22.

[3]Veraldi S. Isoconazole nitrate: a unique broad-spectrum antimicrobial azole effective in the treatment of dermatomycoses, both as monotherapy and in combination with corticosteroids. Mycoses. 2013;56 Suppl 1:3–15.

[4]Veraldi S, Persico MC, Schianchi R. Isoconazole nitrate vs isoconazole nitrate and diflucortolone valerate in the treatment of tinea inguinalis: results of a multicenter retrospective study. J Drugs Dermatol. 2012;11(11):e70–e73.

[5]Wendt H, Kessler J. Antimikrobielle Wirksamkeit des Breitspektrum-Antimykotikums Isoconazolnitrat im Humanversuch [Antimicrobial activity of the broad spectrum antimycotic isoconazole nitrate in humans (author's transl)]. Arzneimittelforschung. 1979;29(5):846–848.

Isoconazole nitrate 实验方案

计算器

存储液制备

1mg

5mg

10mg

1 mM

5 mM

10 mM

2.09mL

0.42mL

0.21mL

10.44mL

2.09mL

1.04mL

20.87mL

4.17mL

2.09mL

Isoconazole nitrate 技术信息

CAS号	24168-96-5
分子式	C₁₈H₁₅Cl₄N₃O₄
分子量	479.141

别名	Isoconazole (nitrate);R 15454;Adestan G 100
运输	蓝冰

存储条件

粉末 Sealed in dry,Room Temperature

液体 -20°C:3-6个月-80°C:12个月

溶解度

DMSO: 105 mg/mL(219.14 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

动物实验配方

硝酸异康唑 /Isoconazole nitrate {[allProObj[0].p_purity_real_show]}

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硝酸异康唑 /Isoconazole nitrate {[allProObj[0].p_purity_real_show]}

Isoconazole nitrate 纯度/质量文件 产品仅供科研

全球学术期刊中引用的产品

Isoconazole nitrate 质控信息

Isoconazole nitrate 生物活性

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Isoconazole nitrate 参考文献

Isoconazole nitrate 实验方案

Isoconazole nitrate 技术信息

最近浏览的产品

大规格询价

摩尔计算器

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总药量计算器

工作液计算器

细胞研究

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确认信息

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