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/ Gluconate sodium

葡萄糖酸钠 /Gluconate sodium {[allProObj[0].p_purity_real_show]}

货号：A548279 同义名： D-葡萄糖酸钠 / D-Gluconic acid sodium salt;Sodium D-gluconate

Sodium Gluconate is the sodium salt of gluconic acid with chelating property.

Gluconate sodium 化学结构 CAS号：527-07-1
Gluconate sodium 化学结构
CAS号：527-07-1
Gluconate sodium 3D分子结构
CAS号：527-07-1
Gluconate sodium 化学结构 CAS号：527-07-1
Gluconate sodium 3D分子结构 CAS号：527-07-1
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Gluconate sodium 纯度/质量文件 产品仅供科研

货号：A548279 标准纯度： {[allProObj[0].p_purity_real_show]}
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Gluconate sodium 生物活性

描述 Sodium Gluconate is a corrosion and scale inhibitor of ordinary steel in simulated cooling water[3]. Sodium gluconate has the potential to increase the solubility of calcium and lactate by forming soluble complexes with calcium and lactate ions, and preventing them from being available for the formation of CLC(calcium lactate crystals) [4]. Compared to the conventional carbon source glucose, the bioconversion of sodium gluconate possessed two distinct advantages: faster utilization rate of sodium gluconate (1.66 g/L per h) compared to glucose (0.996 g/L per h) and no requirement for pH control during fermentation. Sodium gluconate stimulated cell growth when its concentration was below 16 g/L, while it inhibited the cell growth when the concentration was above this concentration. It completely inhibited the cell growth when the concentration was 325 g/L. The high value of both the coefficient of determination (R (2)) and the adjusted R (2) verified the good fit of the model[5]. Dietary sodium gluconate (GNA) promotes butyrate production in the large intestine. The antitumorigenic effect of GNA may involve the stimulation of apoptosis through enhanced butyrate production in the large intestine[6].

Gluconate sodium 临床研究

NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT01216761 Bacteremia Not Applicable Completed - -
NCT00224068 Anemia Phase 4 Completed - -
NCT01216761 - Completed - -

Gluconate sodium 参考文献

[1]Wang D, Wang C, et al. Gluconic acid production by gad mutant of Klebsiella pneumoniae. World J Microbiol Biotechnol. 2016 Aug;32(8):132.

[2]Lu F, Wang Z, et al. A simple novel approach for real-time monitoring of sodium gluconate production by on-line physiological parameters in batch fermentation by Aspergillus niger. Bioresour Technol. 2016 Feb;202:133-41.

[3]Sodium gluconate as corrosion and scale inhibitor of ordinary steel in simulated cooling water

[4]Phadungath C, Metzger LE. Effect of sodium gluconate on the solubility of calcium lactate. J Dairy Sci. 2011 Oct;94(10):4843-9

[5]Wu W, Fan Z. A general inhibition kinetics model for ethanol production using a novel carbon source: sodium gluconate. Bioprocess Biosyst Eng. 2013 Nov;36(11):1631-40

[6]Kameue C, Tsukahara T, Yamada K, Koyama H, Iwasaki Y, Nakayama K, Ushida K. Dietary sodium gluconate protects rats from large bowel cancer by stimulating butyrate production. J Nutr. 2004 Apr;134(4):940-4

Gluconate sodium 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

4.58mL

0.92mL

0.46mL

22.92mL

4.58mL

2.29mL

45.84mL

9.17mL

4.58mL

Gluconate sodium 技术信息

CAS号527-07-1
分子式C6H11NaO7
分子量 218.13
别名 D-葡萄糖酸钠 ;D-Gluconic acid sodium salt;Sodium D-gluconate;D-Gluconate sodium salt
运输蓝冰
存储条件

液体 -20°C:3-6个月-80°C:12个月

粉末 Inert atmosphere,Room Temperature
溶解度

DMSO: 1 mg/mL(4.58 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

H2O: 100 mg/mL(458.43 mM)
动物实验配方

Tags: Gluconate sodium | D-Gluconic acid sodium salt;Sodium D-gluconate;D-Gluconate sodium salt | D-葡萄糖酸钠 | Chelating Agent | AmBeed-信号通路专用抑制剂 | Gluconate sodium 纯度/质量文件 | Gluconate sodium 生物活性 | Gluconate sodium 临床数据 | Gluconate sodium 参考文献 | Gluconate sodium 实验方案 | Gluconate sodium 技术信息

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