产品说明书
Gluconate sodium
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同义名 : | D-葡萄糖酸钠 ;D-Gluconic acid sodium salt;Sodium D-gluconate;D-Gluconate sodium salt |
| CAS号 : | 527-07-1 | |
| 货号 : | A548279 | |
| 分子式 : | C6H11NaO7 | |
| 纯度 : | 99+% | |
| 分子量 : | 218.13 | |
| MDL号 : | MFCD00064210 | |
| 存储条件： |
粉末 Inert atmosphere,Room Temperature 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 1 mg/mL(4.58 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO H2O: 100 mg/mL(458.43 mM) |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Sodium Gluconate is a corrosion and scale inhibitor of ordinary steel in simulated cooling water[3]. Sodium gluconate has the potential to increase the solubility of calcium and lactate by forming soluble complexes with calcium and lactate ions, and preventing them from being available for the formation of CLC(calcium lactate crystals) [4]. Compared to the conventional carbon source glucose, the bioconversion of sodium gluconate possessed two distinct advantages: faster utilization rate of sodium gluconate (1.66 g/L per h) compared to glucose (0.996 g/L per h) and no requirement for pH control during fermentation. Sodium gluconate stimulated cell growth when its concentration was below 16 g/L, while it inhibited the cell growth when the concentration was above this concentration. It completely inhibited the cell growth when the concentration was 325 g/L. The high value of both the coefficient of determination (R (2)) and the adjusted R (2) verified the good fit of the model[5]. Dietary sodium gluconate (GNA) promotes butyrate production in the large intestine. The antitumorigenic effect of GNA may involve the stimulation of apoptosis through enhanced butyrate production in the large intestine[6]. | ||
| 临床研究 | |||||
|---|---|---|---|---|---|
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
| NCT01216761 | Bacteremia | Not Applicable | Completed | - | - |
| NCT00224068 | Anemia | Phase 4 | Completed | - | - |
| NCT01216761 | - | Completed | - | - | |
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
4.58mL 0.92mL 0.46mL |
22.92mL 4.58mL 2.29mL |
45.84mL 9.17mL 4.58mL |
| 参考文献 |
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[3]Sodium gluconate as corrosion and scale inhibitor of ordinary steel in simulated cooling water |