Fadrozole is a selectivearomatase inhibitor that has been introduced in Japan for the treatment of breast cancer.
HazMat Fee +
There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.
Type
HazMat fee for 500 gram (Estimated)
Excepted Quantity
USD 0.00
Limited Quantity
USD 15-60
Inaccessible (Haz class 6.1), Domestic
USD 80+
Inaccessible (Haz class 6.1), International
USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic
USD 100+
Accessible (Haz class 3, 4, 5 or 8), International
Estrogen is a sex hormone implicated in the progression of many diseases. Aromatase is a key enzyme responsible for the biosynthesis of estrogen. Fadrozole is a potent, selective, nonsteroidal inhibitor of aromatase that can be used for the treatment of estrogen-dependent diseases. Fadrozole inhibits aromatase at an IC50 value of 6.4nM. Fadrozole also inhibited the production of estrogen in hamster ovarian slices with an IC50 of 0.03μM. In immature female rats, orally administration of fadrozole inhibited aromatase-mediated, androstenedione-induced uterine hypertrophy with an ED50 value of 0.03mg/kg[2].
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HazMat Fee +
