Enalapril Maleate, the active metabolite of enalapril, is an angiotensin-converting enzyme (ACE) inhibitor. Absorption of enalapril maleate (10 mg, p.o.) was rapid, with peak serum concentrations of enalapril observed 0.5-1.5 h after administration[3]. Moreover, treatment with the ACE inhibitor enalapril maleate improved UVB-induced(ultraviolet B) wrinkles and skin damage in hairless mouse skin[4]. Enalapril maleate and folic acid tablets have a protective effect against CIN (contrast-induced nephropathy) in diabetic rats[5].
Austria
... 展开 >> Medical University of Vienna
Recruiting
Vienna, Austria, 1090
Contact: Marcus Saemann, MD 01/40400/5593 marcus.saemann@meduniwien.ac.at
Sub-Investigator: Johannes Kovarik, MD 收起 <<
Canada, Alberta
... 展开 >>
University of Alberta
Recruiting
Edmonton, Alberta, Canada, T6G 2B7
Contact: Ken S Butcher, MD, PhD 7804072171 ken.butcher@ualberta.ca
Principal Investigator: Ken S Butcher, MD, PhD
Canada, Ontario
Ottawa Hospital Research Institute
Recruiting
Ottawa, Ontario, Canada, K1Y 4E9
Contact: Dar Dowlatshahi 613-761-4709 ddowlat@toh.on.ca
Principal Investigator: Dar Dowlatshahi, MD 收起 <<
Iran, Islamic Republic of
... 展开 >>
Tehran University of Medical Sciences, Vali-asr hospital, Endocrinology and Metabolism Research Center
Tehran, Iran, Islamic Republic of, 13145-784 收起 <<
China, Anhui
... 展开 >> Anqing Research Center of Anhui Medical University Biomedical Institute
Recruiting
Anqing, Anhui, China
Contact: Qing Jiang, MD
China
Peking University First Hosptial
Not yet recruiting
Beijing, China
Contact: Jianping Li, MD
Principal Investigator: Jianping Li, MD
The First People's Hospital of Lianyungang
Recruiting
Lianyungang, China
Contact: Xiaoming Li, MD
Principal Investigator: Xiaoming Li, MD
Second Affiliated Hospital of Nanchang University
Recruiting
Nanchang, China
Contact: Xiaoshu Cheng, MD
Principal Investigator: Xiaoshu Cheng, MD
People's Hospital of Rongcheng
Not yet recruiting
Rongcheng, China
Contact: Chongqian Fang, MD
Principal Investigator: Chongqian Fang, MD 收起 <<
Terminated(lower than expected... 展开 >> enrollment) 收起 <<
-
United States, Massachusetts
... 展开 >>
Children's Hospital Boston
Boston, Massachusetts, United States, 02115
United States, New York
Columbia College of Physicians and Surgeons
New York, New York, United States, 10032
United States, North Carolina
Duke University Medical Center
Durham, North Carolina, United States, 27710
United States, Pennsylvania
Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, United States, 19104
United States, South Carolina
Medical University of South Carolina
Charleston, South Carolina, United States, 29425
United States, Utah
Primary Children's Hospital
Salt Lake City, Utah, United States, 84132
Canada, Ontario
Hospital for Sick Children
Toronto, Ontario, Canada, M5G 1X8 收起 <<
Mexico
... 展开 >> Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Recruiting
Mexico City, Mexico, 14080
Contact: Juan M Mejia-Vilet, MD,MSc 54870900 ext 4142 jmmejia@hotmail.com
Contact: Luis E Morales-Buenrostro, PhD 54870900 ext 4142 luis_buenrostro@yahoo.com.mx 收起 <<
Canada, Alberta
... 展开 >>
University of Calgary
Calgary, Alberta, Canada
University of Alberta
Edmonton, Alberta, Canada, T6G2B7
Grey Nuns Hospital
Edmonton, Alberta, Canada, T6L 5X8
Canada, Ontario
University of Ottawa
Ottawa, Ontario, Canada 收起 <<
Terminated(Because of delay in... 展开 >> approval of the protocol by a number of Ethics Commitees the trial was terminated on March 4, 2010. No patient had received any study drug.) 收起 <<
Sweden
... 展开 >> Dept. of Gastrosurgical Research and Education, Inst. Clinical Sciences, Sahlgrenska University Hospital
Gothenburg, Sweden, S-41345 收起 <<
Brazil
... 展开 >> Marcelo Rodrigues dos Santos
Recruiting
São Paulo, SP, Brazil, 05403-900
Contact: Antonio P Barreto, PhD +55 11 2661-5043 pereira.barreto@incor.usp.br 收起 <<
United States, Alabama
... 展开 >>
Novartis Investigative Site
Fort Payne, Alabama, United States, 35967
United States, California
Novartis Investigative Site
Beverly Hills, California, United States, 90211
Novartis Investigative Site
Stockton, California, United States, 95204
Novartis Investigative Site
West Hills, California, United States, 91307
United States, Florida
Novartis Investigative Site
Doral, Florida, United States, 33126
Novartis Investigative Site
Inverness, Florida, United States, 34452
Novartis Investigative Site
Ormond Beach, Florida, United States, 32174
Novartis Investigative Site
Port Orange, Florida, United States, 32127
United States, Maryland
Novartis Investigative Site
Lutherville, Maryland, United States, 21093
United States, New Jersey
Novartis Investigative Site
East Brunswick, New Jersey, United States, 08816
Novartis Investigative Site
Ridgewood, New Jersey, United States, 07450
United States, South Carolina
Novartis Investigative Site
Columbia, South Carolina, United States, 29203
Novartis Investigative Site
Greenville, South Carolina, United States, 29615
Novartis Investigative Site
Lancaster, South Carolina, United States, 29720
United States, Texas
Novartis Investigative Site
Allen, Texas, United States, 75002-3688
Novartis Investigative Site
McKinney, Texas, United States, 75013
Novartis Investigative Site
New Braunfels, Texas, United States, 78130
Novartis Investigative Site
San Antonio, Texas, United States, 78229
Novartis Investigative Site
San Marcos, Texas, United States, 78666
Novartis Investigative Site
Sherman, Texas, United States, 75092
Novartis Investigative Site
Tomball, Texas, United States, 77375
United States, Virginia
Novartis Investigative Site
Midlothian, Virginia, United States, 23114
United States, Washington
Novartis Investigative Site
Tacoma, Washington, United States, 98405 收起 <<
Hypertension Secondary to Kidn... 展开 >>ey Transplant 收起 <<
Phase 2
Phase 3
Active, not recruiting
December 2018
United States, New York
... 展开 >>
Cohen Children's Medical Center of NY
New Hyde Park, New York, United States, 11040
United States, Pennsylvania
Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, United States, 19104 收起 <<
United States, Massachusetts
... 展开 >>
Children's Hospital Boston
Boston, Massachusetts, United States, 02115
United States, New York
Columbia College of Physicians and Surgeons
New York, New York, United States, 10032
United States, North Carolina
Duke University Medical Center
Durham, North Carolina, United States, 27710
United States, Ohio
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, United States, 45229
United States, Pennsylvania
Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, United States, 19104
United States, South Carolina
Medical University of South Carolina
Charleston, South Carolina, United States, 29425
United States, Utah
Primary Children's Hospital
Salt Lake City, Utah, United States, 84113
United States, Wisconsin
Children's Hospital of Wisconsin
Milwaukee, Wisconsin, United States, 53226
Canada, Ontario
Hospital for Sick Children
Toronto, Ontario, Canada, M5G 1X8 收起 <<
Brazil
... 展开 >> Hospital de Clínicas de Porto Aelgre
Recruiting
Porto Alegre, RS, Brazil, 900035900
Contact: Sandra P Silveiro, MD 55 51 33325188 sandrasilveiro@terra.com.br
Principal Investigator: Sandra P Silveiro, MD
Sub-Investigator: Eduardo G Camargo, MD 收起 <<
Hypertension, Resistant to Con... 展开 >>ventional Therapy 收起 <<
Phase 1
Recruiting
April 2018
United States, Georgia
... 展开 >>
Memorial Family Medicine Center
Recruiting
Savannah, Georgia, United States, 31404
Contact: John Bucheit, Pharm.D. 312-350-8404 bucheit_jd@mercer.edu
Principal Investigator: John Bucheit, Pharm.D.
Sub-Investigator: Cindy Gleit, M.D.
Sub-Investigator: Kathryn Momary, Pharm.D.
Sub-Investigator: Angela Kaylor, R.N.
Sub-Investigator: Daniel Gordon, M.D. 收起 <<
United States, Maryland
... 展开 >>
Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD
Baltimore, Maryland, United States, 21201
United States, Michigan
VA Ann Arbor Healthcare System, Ann Arbor, MI
Ann Arbor, Michigan, United States, 48105
United States, Wisconsin
Clement J. Zablocki VA Medical Center, Milwaukee, WI
Milwaukee, Wisconsin, United States, 53295-1000 收起 <<
United States, New Jersey
... 展开 >>
Sites in USA
East Hanover, New Jersey, United States, 07936
Belgium
Sites in Belgium
Belgium, Belgium
France
Sites in France
France, France
Germany
Sites in Germany
Germany, Germany
Hungary
Sites in Hungary
Hungary, Hungary
India
Sites in India
India, India
Italy
Sites in Italy
Italy, Italy
Poland
Sites in Poland
Poland, Poland
Turkey
Sites in Turkey
Turkey, Turkey 收起 <<
United States, New Jersey
... 展开 >>
Sites in USA
East Hanover, New Jersey, United States, 07936
Belgium
Sites in Belgium
Sites in Belgium, Belgium
France
Sites in France
Sites in France, France
Germany
Sites in Germany
Sites in Germany, Germany
Hungary
Sites in Hungary
Hungary, Hungary
India
Sites in India
Sites in India, India
Italy
Sites in Italy
Sites in Italy, Italy
Poland
Sites in Poland
Poland, Poland
Slovakia
Sites in Slovakia
Slovakia, Slovakia
Sweden
Sites in Sweden
Sites in Sweden, Sweden, 00000
Turkey
Sites in Turkey
Turkey, Turkey 收起 <<
Terminated(Early termination w... 展开 >>as approved due to compelling efficacy of LCZ696 in patients with HF & reduced EF after final pre-specified interim analysis 28-Mar-2014.) 收起 <<
Heart Failure With Reduced Eje... 展开 >>ction Fraction 收起 <<
Phase 3
Terminated(Early termination w... 展开 >>as approved due to compelling efficacy of LCZ696 in patients with HF & reduced EF after final pre-specified interim analysis 28-Mar-2014.) 收起 <<
Cardiovascular Diseases
... 展开 >> Pre-Eclampsia Onset Less Than 37 Weeks (Diagnosis) 收起 <<
Phase 2
Not yet recruiting
November 2020
United Kingdom
... 展开 >> Manchester University NHS Foundation Trust
Not yet recruiting
Manchester, Greater Manchester, United Kingdom, M13 9WL
Contact: Laura Ormesher, MBChB Hon 01617016960 laura.ormesher@manchester.ac.uk 收起 <<
United States, Michigan
... 展开 >>
University of Michigan
Recruiting
Ann Arbor, Michigan, United States, 48109
Contact: Haojie Zhu, PhD 734-763-8449 hjzhu@med.umich.edu 收起 <<
Withdrawn(The sponsor and the ... 展开 >>PIs both agreed that the CSPPT-CKD should be a sub-study of the CSPPT insted of an independent randomized trial.) 收起 <<
August 2014
China, Anhui
... 展开 >> Anqing Branch, Anhui Institute of Biomedical Research
Anqing, Anhui, China, 246000
China, Jiangsu
Lianyungang Center for Advanced Research in Cardiovascular Diseases
Lianyungang, Jiangsu, China, 222003 收起 <<
China, Anhui
... 展开 >> Anqing Branch, Anhui Institute of Biomedical Research
Anqing City, Anhui, China, 246000
China, Jiangsu
Lianyungang Center for Advanced Research in Cardiovascular Diseases
Lianyungang, Jiangsu, China, 222003 收起 <<
Austria
... 展开 >> Medical University of Vienna
Not yet recruiting
Vienna, Austria, 1090
Contact: Christoph Male, Prof,MD,PhD + 43 1 40400 32320 christoph.male@meduniwien.ac.at
Contact: Vanessa Swoboda, MD + 43 1 40400 32320 v.swoboda@live.at
Principal Investigator: Christoph Male, Prof,MD,PhD
Sub-Investigator: Vanessa Swoboda, MD
Hungary
Hungarian Paediatric Heart Centre, Göttsegen Gyorgy Hungarian Institute of Cardiology
Not yet recruiting
Budapest, Hungary, 1095
Contact: András Szatmári, Prof,MD,PhD +36 1 215 1220 szatmari@kardio.hu
Contact: Laszlo Ablonczy, MD +36 1 215 1220 ablonczyl@gmail.com
Principal Investigator: András Szatmári, Prof,MD,PhD
Sub-Investigator: Laszlo Ablonczy, MD
Netherlands
Sophia Children's Hospital, Erasmus MC
Not yet recruiting
Rotterdam, Netherlands, 3015 CN
Contact: Michiel Dalinghaus, MD,PhD +3110-7040704 'Michiel Dalinghaus'
Contact: Tjitske van der Zanden +3110-7040704 t.vanderzanden@erasmusmc.nl
Principal Investigator: Michiel Dalinghaus, MD,PhD
Sub-Investigator: Marijke Van der Meulen, MD,PjD
Wilhelmina Children's Hospital, University Medical Center Utrecht
Not yet recruiting
Utrecht, Netherlands, 3584 CX
Contact: J.M.P. J. Breur, MD,PhD + 31 8875 540 02 h.breur@umcutrecht.nl
Principal Investigator: J.M.P. J. Breur, MD,PhD
Serbia
Univerzitetska Dečja Klinika
Not yet recruiting
Belgrade, Serbia, 11129
Contact: Milica Bajcetic, Prof,MD,PhD + 38 1112060716 milica.bajcetic@udk.bg.ac.rs
Contact: Ida Jovanovic, Prof,MD,PhD + 38 1112060716 idaj@rcub.bg.ac.rs
Principal Investigator: Ida Jovanovic, Prof,MD,PhD
United Kingdom
Great Ormond Street Hospital for Children NHS Trust
Not yet recruiting
London, United Kingdom, WC1N 3JH
Contact: Michael Burch, Prof,MD,PhD +44 020 7405 9200 michael.burch@gosh.nhs.uk
Principal Investigator: Michael Burch, Prof,MD,PhD 收起 <<
Austria
... 展开 >> Medical University of Vienna
Not yet recruiting
Vienna, Austria, 1090
Contact: Christoph Male, Prof,MD,PhD + 43 1 40400 32320 christoph.male@meduniwien.ac.at
Contact: Vanessa Swoboda, MD + 43 1 40400 32320 v.swoboda@live.at
Principal Investigator: Christoph Male, Prof,MD,PhD
Sub-Investigator: Vanessa Swoboda, MD
Hungary
Hungarian Paediatric Heart Centre,Göttsegen Gyorgy Hungarian Institute of Cardiology
Not yet recruiting
Budapest, Hungary, 1095
Contact: András Szatmári, Prof,MD,PhD +36 1 215 1220 szatmari@kardio.hu
Contact: Laszlo Ablonczy, MD +36 1 215 1220 'Laszlo Ablonczy'
Principal Investigator: András Szatmári, Prof,MD,PhD
Sub-Investigator: Laszlo Ablonczy, MD
Netherlands
Sophia Children's Hospital Erasmus MC
Not yet recruiting
Rotterdam, Netherlands, 3015 CN
Contact: Saskia N. de Wildt, MD,PhD +31 10 7040704 s.dewildt@erasmusmc.nl
Contact: Tjitske van der Zanden +31 10 7040704 t.vanderzanden@erasmusmc.nl
Principal Investigator: Michiel Dalinghaus, MD,PhD
Sub-Investigator: Marijke Van der Meulen, MD,PhD
Wilhelmina Children's Hospital, University Medical Center Utrecht
Not yet recruiting
Utrecht, Netherlands, 3584 CX
Contact: J.M.P. J. Breur, MD,PhD + 31 8875 540 02 h.breur@umcutrecht.nl
Principal Investigator: J.M.P. J. Breur, MD,PhD
Serbia
Univerzitetska Dečja Klinika
Not yet recruiting
Belgrade, Serbia, 11129
Contact: Milica Bajcetic, Prof,MD,PhD +38 1112060716 milica.bajcetic@udk.bg.ac.rs
Contact: Ida Jovanovic, Prof,MD,PhD + 38 1112060716 idaj@rcub.bg.ac.rs
Principal Investigator: Ida Jovanovic, Prof,MD,PhD
United Kingdom
Great Ormond Street Hospital for Children NHS Trust
Not yet recruiting
London, United Kingdom, WC1N 3JH
Contact: Michael Burch, Prof,MD,PhD +44 020 7405 9200 michael.burch@gosh.nhs.uk
Principal Investigator: Michael Burch, Prof,MD,PhD 收起 <<
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