货号:A808091 同义名: Bay 1161909;Mps1-IN-5
BAY 1161909 inhibits Mps1 kinase activity with IC50 of < 1 nM when assay with 10 μM ATP, with IC50 of < 1.9 nM when assay with 2 mM ATP.
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描述 | BAY 1161909 is a highly potent inhibitor of Mps1, exhibiting an IC50 of < 1 nM. Additionally, BAY 1161909 demonstrates anti-tumor activity by inhibiting the proliferation of Hela cells, with an IC50 of < 400 nM[1]. |
体外研究 | BAY 1161909 is a highly potent inhibitor of Mps1, exhibiting an IC50 of < 1 nM. Additionally, BAY 1161909 demonstrates anti-tumor activity by inhibiting the proliferation of Hela cells, with an IC50 of < 400 nM[1]. |
计算器 | ||||
存储液制备 | 1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
1.79mL 0.36mL 0.18mL |
8.93mL 1.79mL 0.89mL |
17.87mL 3.57mL 1.79mL |
CAS号 | 1443763-60-7 |
分子式 | C29H26FN5O4S |
分子量 | 559.611 |
别名 | Bay 1161909;Mps1-IN-5 |
运输 | 蓝冰 |
存储条件 |
粉末 Keep in dark place,Sealed in dry,2-8°C 液体 -20°C:3-6个月-80°C:12个月 |
溶解度 |
DMSO: 35 mg/mL(62.54 mM),注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO |
动物实验配方 |