产品说明书
Empesertib
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同义名 : | Bay 1161909;Mps1-IN-5 |
| CAS号 : | 1443763-60-7 | |
| 货号 : | A808091 | |
| 分子式 : | C29H26FN5O4S | |
| 纯度 : | 99%+ | |
| 分子量 : | 559.611 | |
| MDL号 : | MFCD28902188 | |
| 存储条件： |
粉末 Keep in dark place,Sealed in dry,2-8°C 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 35 mg/mL(62.54 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | BAY 1161909 is a highly potent inhibitor of Mps1, exhibiting an IC50 of < 1 nM. Additionally, BAY 1161909 demonstrates anti-tumor activity by inhibiting the proliferation of Hela cells, with an IC50 of < 400 nM[1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
1.79mL 0.36mL 0.18mL |
8.93mL 1.79mL 0.89mL |
17.87mL 3.57mL 1.79mL |
| 参考文献 |
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[1]SCHULZE, Volker, et al. PRODRUG DERIVATIVES OF SUBSTITUTED TRIAZOLOPYRIDINES. WO2014198647A2 |