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首页 / 抑制剂/激动剂 / G蛋白偶联受体/G蛋白 / 前列腺素受体 / Dinoprost tromethamine salt

地诺前列素氨丁三醇 /Dinoprost tromethamine salt {[allProObj[0].p_purity_real_show]}

货号：A385706 同义名： 地诺前列素 / Prostaglandin F2α THAM;Prostaglandin F2α tromethamine salt

Dinoprost tromethamine is a natural prostaglandin used as an abortifacient.

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Dinoprost tromethamine salt 化学结构 CAS号：38562-01-5
Dinoprost tromethamine salt 化学结构
CAS号：38562-01-5
Dinoprost tromethamine salt 3D分子结构
CAS号：38562-01-5
Dinoprost tromethamine salt 化学结构 CAS号：38562-01-5
Dinoprost tromethamine salt 3D分子结构 CAS号：38562-01-5
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Dinoprost tromethamine salt 纯度/质量文件 产品仅供科研

货号：A385706 标准纯度： {[allProObj[0].p_purity_real_show]}
批次查询： 批次纯度:

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Dinoprost tromethamine salt 生物活性

描述 Dinoprost tromethamine salt, also known as Prostaglandin F2α tromethamine salt, is a potent agonist of the prostaglandin F (PGF) receptor (FP receptor) that can be administered orally. It acts as a luteolytic hormone primarily synthesized in the endometrial luminal epithelium and corpus luteum (CL). Dinoprost tromethamine salt plays a pivotal role in initiating and advancing labor [1][2].
体外研究

Dinoprost tromethamine salt (Prostaglandin F2α tromethamine salt; 1 μM; for 24 hours), triggers endoplasmic reticulum (ER) stress, autophagy, and apoptosis in goat luteal cells [1].

Dinoprost tromethamine salt (1 μM; for 24 hours) markedly upregulates the expression of GRP78 and UPR sensors [1].

Dinoprost tromethamine salt 临床研究

NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT02052908 Lynch Syndrome Phase 1 Active, not recruiting - United States, Massachusetts ... 展开 >> Brigham and Women's Hospital Boston, Massachusetts, United States, 02115 United States, Michigan University of Michigan Comprehensive Cancer Center Ann Arbor, Michigan, United States, 48109 United States, Texas M D Anderson Cancer Center Houston, Texas, United States, 77030 United States, Utah Huntsman Cancer Institute/University of Utah Salt Lake City, Utah, United States, 84112 收起 <<
NCT01974674 Patients With Type 1 Diabetes Phase 2 Recruiting January 2022 France ... 展开 >> Saint Louis hospital Recruiting Paris, Ile de France, France, 75010 Contact: Pierre CATTAN, MD PhD    33 1 42494786    pierre.cattan@sls.aphp.fr 收起 <<
NCT01688154 Triglyceride Metabolism ... 展开 >> Cardiovascular Function 收起 << Not Applicable Completed - Spain ... 展开 >> CTNS Reus, Tarragona, Spain, 43204 Technological Center of Nutrition and Health (CTNS) Reus, Tarragona, Spain, 43204 收起 <<

Dinoprost tromethamine salt 参考文献

[1]Hagen Thieme, et al. Endothelin antagonism: effects of FP receptor agonists prostaglandin F2alpha and fluprostenol on trabecular meshwork contractility. Invest Ophthalmol Vis Sci. 2006 Mar;47(3):938-45.

[2]Xin Wen, et al. Prostaglandin F2α Induces Goat Corpus Luteum Regression via Endoplasmic Reticulum Stress and Autophagy. Front Physiol. 2020 Sep 11;11:868.

Dinoprost tromethamine salt 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.10mL

0.42mL

0.21mL

10.51mL

2.10mL

1.05mL

21.03mL

4.21mL

2.10mL

Dinoprost tromethamine salt 技术信息

CAS号38562-01-5
分子式C24H45NO8
分子量 475.616
别名 地诺前列素 ;Prostaglandin F2α THAM;Prostaglandin F2α tromethamine salt;Prostamate;U 14585;PGF2α;Dinoprost;Prostaglandin F2α (tromethamine salt);Dinoprost Trometamol;Prostin F2 alpha;Zinoprost;PGF2-alpha tham;Dinolytic;Dinoprost tromethamine;PGF2α THAM
运输蓝冰
存储条件

液体 -20°C:3-6个月-80°C:12个月

粉末 Inert atmosphere,Store in freezer, under -20°C
溶解度

DMSO: 105 mg/mL(220.77 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

H2O: 100 mg/mL(210.25 mM)
动物实验配方

Tags: Dinoprost | 38562-01-5 | Prostaglandin F2α | PGF2α THAM | Prostaglandin F2α THAM | FP Receptor Agonist | GPCR/G Protein | Metabolic Enzyme/Protease | Autophagy | Apoptosis | Prostaglandin Receptor | Endogenous Metabolite | Autophagy | Apoptosis | 仅供科研使用 | AmBeed-信号通路专用抑制剂 | Dinoprost tromethamine salt 纯度/质量文件 | Dinoprost tromethamine salt 生物活性 | Dinoprost tromethamine salt 临床数据 | Dinoprost tromethamine salt 参考文献 | Dinoprost tromethamine salt 实验方案 | Dinoprost tromethamine salt 技术信息

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