产品说明书
Dinoprost tromethamine salt
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同义名 : | 地诺前列素 ;Prostaglandin F2α THAM;Prostaglandin F2α tromethamine salt;Prostamate;U 14585;PGF2α;Dinoprost;Prostaglandin F2α (tromethamine salt);Dinoprost Trometamol;Prostin F2 alpha;Zinoprost;PGF2-alpha tham;Dinolytic;Dinoprost tromethamine;PGF2α THAM |
| CAS号 : | 38562-01-5 | |
| 货号 : | A385706 | |
| 分子式 : | C24H45NO8 | |
| 纯度 : | 98% | |
| 分子量 : | 475.616 | |
| MDL号 : | MFCD00077863 | |
| 存储条件： |
粉末 Inert atmosphere,Store in freezer, under -20°C 液体 -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 105 mg/mL(220.77 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO H2O: 100 mg/mL(210.25 mM) |
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| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Dinoprost tromethamine salt, also known as Prostaglandin F2α tromethamine salt, is a potent agonist of the prostaglandin F (PGF) receptor (FP receptor) that can be administered orally. It acts as a luteolytic hormone primarily synthesized in the endometrial luminal epithelium and corpus luteum (CL). Dinoprost tromethamine salt plays a pivotal role in initiating and advancing labor [1][2]. | ||
| 临床研究 | |||||
|---|---|---|---|---|---|
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
| NCT02052908 | Lynch Syndrome | Phase 1 | Active, not recruiting | - | United States, Massachusetts ... 展开 >> Brigham and Women's Hospital Boston, Massachusetts, United States, 02115 United States, Michigan University of Michigan Comprehensive Cancer Center Ann Arbor, Michigan, United States, 48109 United States, Texas M D Anderson Cancer Center Houston, Texas, United States, 77030 United States, Utah Huntsman Cancer Institute/University of Utah Salt Lake City, Utah, United States, 84112 收起 << |
| NCT01974674 | Patients With Type 1 Diabetes | Phase 2 | Recruiting | January 2022 | France ... 展开 >> Saint Louis hospital Recruiting Paris, Ile de France, France, 75010 Contact: Pierre CATTAN, MD PhD 33 1 42494786 pierre.cattan@sls.aphp.fr 收起 << |
| NCT01688154 | Triglyceride Metabolism ... 展开 >> Cardiovascular Function 收起 << | Not Applicable | Completed | - | Spain ... 展开 >> CTNS Reus, Tarragona, Spain, 43204 Technological Center of Nutrition and Health (CTNS) Reus, Tarragona, Spain, 43204 收起 << |
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
2.10mL 0.42mL 0.21mL |
10.51mL 2.10mL 1.05mL |
21.03mL 4.21mL 2.10mL |
| 参考文献 |
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